Sentences with phrase «controlling tumor metabolism»

Not exact matches

Investigators focused on the tumor suppressor liver kinase B1 (LKB1), a protein that controls cell growth and metabolism.

LKB1, originally identified as a tumor suppressor protein, is currently thought as a critical regulator of cellular metabolism and growth by controlling the activity of AMP - activated protein kinase (AMPK) and also 12 other kinases that are closely related to AMPK.

Results published by the Altieri laboratory demonstrated that these molecules accumulate in mitochondria of tumor cells, where they physically interact with components of the organelle permeability transition as well as with a number of regulators of bioenergetics, including the control of protein production, lipid metabolism and ATP generation.

In cats, brain inflammations (encephalitis), as yet unexplained degenerative changes in the cat's hippocampal portion of the brain (ref1, ref2), exposure to toxic substances, flea and tick control products, traumatic brain injuries, abnormal body metabolism, brain tumors and FIP account for most of the rest.