Sentences with phrase «controls early cell»

The pair discovered a swath of cells in frog embryos that controls early cell differentiation.

Not exact matches

Duke University biologist Pelin Volkan and colleagues have identified a set of genetic control switches that interact early in a fly's development to generate dozens of types of olfactory neurons, specialized nerve cells for smell.

A Johns Hopkins study earlier this year confirmed that the Zika virus works by attacking the brain's cortical neural progenitor cells that eventually become the brain's cortex that controls many higher functions.

Once stem cells can be grown and differentiated in a controlled way to replace degenerated cells and repair tissues, medical science may then be able to diagnose and cure many intractable diseases at their earliest stages, such as type 1 diabetes, Parkinson's disease, various cardiovascular diseases, liver disease, and cancer.

Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, might damage muscle - controlling nerve cells in the brain earlier in the disease process than previously known, according to research from the Cedars - Sinai Board of Governors Regenerative Medicine Institute.

This result reflected earlier findings that ILC and T cell subclasses produce similar sets of cytokines, but also revealed differences in how the two cell types control the activities of these key immune response genes.

In the case of planarians, the gene egr - 4 seems to perform an early control of cell proliferation as a response to amputation, and be involved later in the early differentiation of brain during regeneration.

The authors uncover the cellular and molecular mechanisms, as well as the gene network regulated by Sox9 during the early steps of skin tumor initiation and demonstrates that Sox9 controls the long term maintenance and expansion of oncogene expressing cells by promoting self - renewing division and inhibiting differentiation.

That knowledge, combined with earlier research by Rey and others, could hint at novel ways to block the virus from infecting cells, says virologist John Roehrig of the Centers for Disease Control and Prevention's Division of Vector - Borne Diseases in Fort Collins, Colorado.

The technique relies on optogenetics, a method of controlling brain cells through bursts of light developed by HHMI early career scientist Karl Deisseroth at Stanford University.

The study, published online today in PLoS Genetics, is the first to suggest that low, brief exposures to bisphenol - A, or other estrogens such as those used in birth control but found as water contaminants, early in life can alter the stem cells responsible for producing sperm later in life.

Positive controls consisted of C57BL / 6 mice that had been subcutaneously (SC) immunized with 1 × 107 BALB / c spleen cells 14 days earlier.

Briefly, single - cell suspensions of splenocytes were prepared from either experimental or control host strain mice, as described earlier.

Morphological and immunocytochemical characteristics indicate the yield of early progenitors and represent a quality control for human mesenchymal stem cell culturing.

Pro-apoptotic bax and bak control beta - cell death and early endoplasmic reticulum stress signalling.

Percent eosinophils was lower in these vaccinated animals (mean 1 — 3.2 %) than had been seen in animals given VLP vaccines in the earlier study (mean 13.2 ± 9.6 % and 22 ± 9.9 % of cells for VLP with PBS or alum, respectively in that study) but no (0 %) eosinophils were seen in the lung infiltrates of control animals in this experiment.

Stereotactic body radiotherapy (SABR) can provide acceptable local control in patients with medically operable and inoperable early stage non-small cell lung cancer

Here we controlled for some of the features that differed among the earlier studies, and analyzed both the survival and expansion of naive CD4 + T cells transferred into MHC syngeneic, allogeneic, or MHC negative environments.

Studying the epigenetic setting of germ cells allows investigating several crucial aspects of mammalian biology such as transposon control, genomic imprinting and early lineage commitment.

Early efforts centered on defining how HIV - specific CD4 + T cells contribute to control of viral infection.

The authors first stably transduced freshly derived multipotent early passage hDPSCs with a PDGF - BB expression vector, generating cells that displayed heightened proliferation when compared to control hDPSCs.

CD4ζ - hESC - NKs cells were observed in peripheral blood early at day 6 at which point CD4 T - cell counts rose compared in NK treated mice compared to control, which gained significance by day 12, demonstrating suppression of HIV activity.

In rare cases, DBA in boys can be due to a mutation in a gene called GATA - 1, which controls the earliest steps of red blood cell production.

A fast track «Hot Start» process was implemented to launch the European Bank for Induced Pluripotent Stem Cells (EBiSC) to provide early release of a range of established control and disease linked human induced pluripotent stem cell (hiPSC) lines.

It has also been reported that Kap1 controls endogenous retroelements during early embryonic development and in embryonic stem cells but not in adult fibroblasts [45].

Specifically the disputed question is whether Toddler acts early, to enhance Nodal signaling, and therefore to specify endoderm cells; or, alternatively, whether it acts later, to control the migration of mesendoderm.

Early spaying may therefore, reduce occurrence of malignant lesions because the procedure removes the source of the hormones that cause some mammary cells to lose growth control, which puts these dividing cells at high risk for mutation and malignant transformation by environmental carcinogens.In fact, recent reports have identified activation of a specific oncogene in a number of canine mammary tumors.

GRPU is a very serious disease, in which early detection is critical — with early detection, dogs can be placed on lifetime daily anti-inflammatory medications and a special canine antioxidant vision supplement to help control inflammation and also to help support the health of all the cells of the eyes, and the immune system too.

In earlier works, Jukkala has drawn on postmodern abstractionists like Peter Halley, with his cells and conduits that allude to systems of corporate control, and extended his representational agenda, fragmenting rectilinear shapes into pixelated grids with jazzy patterns that might be robotic figures or electronic graphics.