Sentences with phrase «conventional chemotherapy»

A total of 46 patients received GO alone or in combination with conventional chemotherapy.

Some choose to use holistic / alternative therapy alone or in conjunction with the more conventional chemotherapy treatments.

Some of these agents appear to halt cancer growth, which would then allow conventional chemotherapy treatments to work more effectively.

The more than 1,600 patients in the study were followed for almost 16 months and were also treated with conventional chemotherapy.

Current treatments for acute lymphoblastic leukemia (ALL), an aggressive form of blood cancer, include conventional chemotherapy drugs that inhibit DNA synthesis.

Her doctor suggested Erbitux — a proven cancer drug that targets cancer cells exclusively, unlike conventional chemotherapies that more crudely kill all fast - growing cells in the body — and Aucoin went to a clinic to begin treatment.

In fact, we found the inhibition of acidification of endosomes enhances the effect of conventional chemotherapy in mice, «says Dr. Lluís Espinosa.

June - Koo Lee, M.D., of Seoul National University Hospital, Seoul, Republic of Korea, and colleagues performed a meta - analysis of randomized controlled trials that compared first - generation EGFR TKI (erlotinib and gefitinib) treatment with conventional chemotherapy in patients with advanced NSCLC without mutation of the EGFR gene.

«There are currently many exciting therapies including conventional chemotherapies, small molecule inhibitor tyrosine kinase inhibitors and immune modulating therapies under development in follicular lymphoma,» Westin told Cancer Network.

Only about 20 - 30 % have tumour shrinkage after conventional chemotherapy and survival is usually less than one year.

Unlike targeted therapy and conventional chemotherapy for most malignancies, immunotherapy has the advantage of providing long - term clinical benefit in some patients.

The discovery is significant because the drug halts the propagation of cancer stem cells without causing the toxic side - effects normally associated with more conventional chemotherapy.

In the phase II CIRCCa trial, researchers compared two groups of patients with relapsed or metastatic cervical cancer given conventional chemotherapy with carboplatin and paclitaxel plus either cediranib (34 patients) or an identical looking placebo tablet (35 patients).

Conventional chemotherapy agents work by indiscriminately poisoning and killing rapidly - dividing cells, including cancer cells, by damaging cellular machinery and DNA.

Integrating natural therapies including diet and exercise into conventional chemotherapy and radiation treatment, Dr. Alschuler emerged from her experience feeling healthier and more revitalized than ever before.

If you are undergoing conventional chemotherapy or radiation therapies, fasting at least 14 hours before treatment may help improve outcomes and mitigate side effects.

TNBC is a type of cancer that defies conventional chemotherapy and radiation.

Prognosis — Conventional chemotherapy results in total remission in approximately 60 - 90 % of cases with a median survival time of 6 - 12 months.

«Identifying a cancer driver is crucial for cancer treatment because it allows the use of targeted therapies, which have less side - effects than conventional chemotherapy drugs, against a particular protein,» said Kurokawa.

Unlike conventional chemotherapies and radiation that indiscriminately eradicate fast - growing tissues and ravage people's bodies with side effects, new therapies specifically target tumors using tailored cells from individual patients.

Therefore, a novel therapeutic approach in inflammatory breast cancer could involve a combination of conventional chemotherapy with small - molecule inhibitors of the Cdk2 cell cycle kinase.

FLT3 mutations are more common in patients with normal karyotype and appear to be associated with a higher rate of relapse after conventional chemotherapy.

Studies have shown that TKI treatment is better than conventional chemotherapy in terms of progression - free survival (PFS) among patients with these EGFR mutations; it is not clear that EGFR TKIs are as effective as standard chemotherapy in patients without EGFR mutations, according to background information in the article

The anti-cancer effect of the antimalarial agent chloroquine when combined with conventional chemotherapy has been well documented in experimental animal models.

One of the four patients whose metastatic bile duct tumor failed to respond to conventional chemotherapy was recruited to an FGFR inhibitor trial, and he is currently undergoing treatment, according to Chinnaiyan.

Combining the drug gemtuzumab ozogamicin (GO) with conventional chemotherapy may improve the outcome of bone marrow transplantation for some children battling high - risk acute myeloid leukemia (AML), according to a study led by St. Jude Children's Research Hospital.

They found that CD44 + / CD24 - / Low cancer stem cells (CSCs) were resistant to conventional chemotherapy but were sensitive to SU9516, which is a specific cyclin - dependent kinase 2 (Cdk2) inhibitor.

The research involved engineering nanostructures containing both gold and cisplatin, a conventional chemotherapy drug.

Although she was ineligible for the trial, he put her on turkey tail capsules to supplement her conventional chemotherapy drugs, Taxol and Herceptin.

A transplant of hematopoietic stem cells attempts to cure patients with certain cancers and other serious illnesses that have not responded to conventional chemotherapies.

The Tampa trial involves 27 patients with aggressive skin cancers such as malignant melanoma and basal cell carcinoma that failed to respond to conventional chemotherapy.

According to Crandell, the treatment appears to do much less harm to normal cells than conventional chemotherapy.

Papers detailing these results, the first research ever to look at the synergy of immunotherapy with conventional chemotherapy, have been submitted to peer - reviewed journals, and Black thinks publication will generate considerable excitement among cancer researchers, who have until now seen mostly disappointing results from vaccine therapies against other cancers.

This patient was a 68 - year - old woman with DLBCL that had not responded either to conventional chemotherapies or to a stem - cell transplant, a situation that usually leads to a life expectancy of less than six months.

A new therapeutic approach tested by a team from Maisonneuve - Rosemont Hospital (CIUSSS - EST, Montreal) and the University of Montreal gives promising results for the treatment of multiple myeloma, a cancer of the bone marrow currently considered incurable with conventional chemotherapy and for which the average life expectancy is about 6 or 7 years.

Among patients with advanced non-small cell lung cancer without a mutation of a certain gene (EGFR), conventional chemotherapy, compared with treatment using epidermal growth factor receptor tyrosine kinase inhibitors, was associated with improvement in survival without progression of the cancer, but not with overall survival, according to a study in the April 9 issue of JAMA.

''... this study suggests that, in patients with WT EGFR tumors, conventional chemotherapy could be a preferable treatment option over EGFR TKI, although this recommendation can not be conclusive because the overall comparisons were not based on randomization.

• Platinum - Resistant — these are patients whose disease recurred within six months of conventional chemotherapy (using the drugs cisplatin or carboplatin) and are generally less responsive to subsequent treatments and have not responded as well to PARP inhibitors.

They embedded cephalexin — marketed as Keflexa and Keftaba — in a polymer containing tin and tested it against two cell lines, both obtained from ovarian cancer patients who had not responded to conventional chemotherapy.

Unlike conventional chemotherapies, this new approach to cancer therapy has fewer toxic side effects, and gives hope for a cancer treatment that is gentler on young bodies.

«Our new type of treatment only targets metastatic tissue, which enables us to avoid some of conventional chemotherapy's unwanted side effects,» said Zhao, who is a member of the Chao Family Comprehensive Cancer Center and the Sue & Bill Gross Stem Cell Research Center at UCI.

«The idea is a two - hit strategy,» Peter said, «hit them first with the microRNA and make those drug - resistant cells sensitive again, then hit them again with low levels of conventional chemotherapy.»

«The advantage to this approach is that, unlike conventional chemotherapy, it doesn't harm normal cells, so it should have far fewer toxic side effects.»

In addition to conventional chemotherapy and radiation, we also offer clinical trials and / or targeted therapies for these tumors.

In the bone marrow microenvironment, CLL cells are protected from spontaneous or drug - induced apoptosis, resulting in resistance to conventional chemotherapy.

In some cancers the correlation between the presence of Pgp function and non-response to chemotherapy has been established and the use of agents that block Pgp functiton has begun to yield promising results in combination with conventional chemotherapy.

A total of 16 patients with stage IV or recurrent NSCLC received both conventional chemotherapy as well as one or more of the available HER2 therapies (some received more than one, yielding 22 total therapies to evaluate).

Our data highlight key roles for MAP3K8 in high - grade ovarian cancers and indicate that MEK inhibitors could be a useful treatment strategy, in combination with conventional chemotherapy (Gruosso, Nature Communications, 2015).

The new paradigm offers a distinction from the conventional chemotherapy approach and represents the first defined development guidelines in this field.