An emerging strategy in early drug discovery entails using fragments, i.e. molecules smaller than
conventional drug candidates, as starting points for design of novel therapeutic compounds.
Not exact matches
Carmot is applying an innovative technology, Chemotype Evolution, to overcome the limitations of
conventional discovery technologies and identify superior
drug candidates for challenging therapeutic targets.
Carmot is applying a transformative technology, Chemotype Evolution, to overcome the limitations of
conventional discovery technologies and to identify superior
drug candidates for challenging therapeutic targets.
We currently evaluate the therapeutic benefits as well as the toxicity of
drug candidates in spheroids by means of
conventional fluorescence microscopy as well as LSFM and many different biochemical and molecular biology - based assays (Ansari et al. 2013; Wenzel et al. 2014; Pampaloni & Stelzer 2010).