Unfortunately, not every gene product can be targeted with
conventional small molecule inhibitors.
Carmot's vision is to become a leader in drug discovery by unlocking novel therapeutic target space not currently accessible to
conventional small molecule technologies.
Not exact matches
Therefore, a novel therapeutic approach in inflammatory breast cancer could involve a combination of
conventional chemotherapy with
small -
molecule inhibitors of the Cdk2 cell cycle kinase.
Mezey says that
conventional techniques for drawing electron clouds have been restricted to
molecules containing around 100 atoms, such as vitamins and
small peptides.
«Sodium ions are much
smaller than the hydrogen protons bound to oxygen
molecules in the water in our bodies which are mapped by
conventional MRI.
At the moment, I don't think anyone has much of an idea on how to identify good
small molecule candidates with
conventional medicinal chemistry methods (though I'm intrigued to hear that you have some thoughts, AH!).
Orders of magnitude more sensitive than
conventional Raman microscopy, they allow mapping of 3D distributions of
small molecules, such as metabolites and drugs, as well as tumor identification in tissues, which open many exciting new possibilities for biology and medicine.
An emerging strategy in early drug discovery entails using fragments, i.e.
molecules smaller than
conventional drug candidates, as starting points for design of novel therapeutic compounds.
The team tested the graphene membranes by passing water, salts and other
molecules through them, and found the material's performance «comparable to graphene membranes made using
conventional,
small - batch approaches.»
This means that a
conventional protein source is used but the protein is broken down into
molecules too
small to excite the immune system.