Sentences with phrase «convert calcidiol»
«These types of cancer locally convert calcidiol to calcitriol, a vitamin D metabolite that has significant anti-cancer activity in preclinical models, and could prove to be an important adjunct therapy.»
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However, once Vitamin D enters the body, it is then transported through the bloodstream to the liver where it is converted into the prohormone calcidiol.
While 7 - dehydrocholesterol is tucked tightly within the lipids of skin cell membranes, previtamin D3 is an unstable compound that over a brief period of time converts into vitamin D3, causing it to be released from the cell membrane.12 Vitamin D3 then travels into the blood where it binds to vitamin D - binding protein (DBP).16 Eventually, it is delivered to the liver where it is converted into its primary storage form, calcidiol, which is likewise transported in the blood by DBP.8
If there's enough calcidiol left in the tank after the calcium duties, it gets sent to other tissues in the body to be converted into more calcitriol to fulfill even more roles.