Sentences with phrase «convert embryonic cells»
In 2009, from experiments at the RIKEN Center for Developmental Biology in Kobe, Japan, he found that when culture conditions are right, adding a single ingredient — bone morphogenetic protein 4 (Bmp4)-- with precise timing is enough to convert embryonic cells to PGCs.
https://www.scientificamerican.com/ Not exact matches
The ultimate goal of our laboratory is to generate ES - like cells directly from somatic cells by nuclear reprogramming... which converts adult cells back into embryonic state.
Ten years ago, the team at Advanced Cell Technology announced that it had successfully converted human embryonic stem cells into retinal pigment epithelial cells.
But to convert adult cells into embryonic - like cells means genetic reprogramming, for example with a virus, and the reprogrammed cells do not yet match embryonic stem cells.
Hayashi then drew on other research showing that one key regulatory molecule (activin A) and a growth factor (basic fibroblast growth factor) could convert cultured early embryonic stem cells into cells akin to epiblasts.
This technology was pioneered by Shinya Yamanaka, who showed that the introduction of four specific proteins that are essential during early embryonic development could be used to convert adult cells into pluripotent cells.
Clearly, no one is going to convert embryonic stem cells into neurons and reprogram them into induced stem cells — that would be too time - consuming and expensive.
Karim Nayernia of the University of Newcastle, UK, and his colleagues treated male embryonic stem cells (ESCs) with a range of substances, which converted them first into germline stem cells and then into spermatogonial stem cells.
Other researchers had successfully used a similar process to turn skin cells into embryonic - like cells called induced pluripotent stem cells, and then grow those iPS cells into nerve cells, but Wernig's lab was the first to convert skin cells directly into nerve cells without the intermediate iPS cell step.
They successfully converted mature mouse skin cells into what they called induced pluripotent stem (iPS) cells that had the same wide - open potential as embryonic stem cells — which the researchers showed by turning their iPS cells into nerve and connective tissue cells.
His lab is currently working to convert human embryonic stem cells to dopamine neurons.
«Discovery of a gene that could convert human embryonic stem cells into myocardial cells would be golden,» said Didier Stainier, PhD, UCSF assistant professor of biochemistry and biophysics, the senior author of the UCSF study and a pioneer in the study of heart development in the transparent zebrafish embryo.
Pluripotent stem cells — those, like embryonic stem cells, that give rise to almost every type of cell in the body — can be converted into the different classes of retinal cells necessary for vision, according to a new, RPB - supported study from researchers at SUNY Upstate Medical University in Syracuse, N.Y.
However, one line with 4 % carryover showed a wide drift when converted into an embryonic stem cell (hES) line, with some clones eventually having around 50 % of the original mitochondrial type.
As one example, using insights from embryonic development, Jessell has been able to convert embryonic stem cells into functioning motor neurons, facilitating the discovery of medicines to treat such diseases.
What she has shown is you can make mouse embryonic stem cells convert unidirectionally to trophoblasts by activating a single gene.