Their study examined the ways two pathogens work together, finding that
cooperativity between contagion processes is likely to make the spread of contagious infections more severe.
For sufficiently
strong cooperativity, increasing the baseline reproduction number of one or both agents produced abrupt, discontinuous outbreak transitions and multi-stability.
We wanted to discover what basic dynamic features you could expect in a cooperative contagion process, and the extent to
which cooperativity changes the classic outbreak scenario.»
It is quite striking that
such cooperativity is not limited to adjacent or nearby sites but involves relatively distant sites and even well separated nanoparticles, he remarks.
Proinflammatory cytokines enhance estrogen - dependent expression of the multidrug transporter gene ABCG2 through estrogen receptor and NF -LCB- kappa -RCB-
B cooperativity at adjacent response elements.
He also uncovered a new mechanism of active -
site cooperativity distinct from allostery in enzyme activity and elucidated unexpected mechanisms of active - site coupling in his multienzyme complexes based on motile protein domains.
They discovered that
cooperativity between contagion processes generates a variety of interesting properties that are absent in single agent dynamics.
«I know the location, but I also know the commitment [to science] and
the cooperativity that works there.
Results from these and other studies are yielding important insights into
the cooperativity effects in hydrogen bonding, aqueous solvation, and hydrogen - bond network rearrangement dynamics, which promise to enhance our understanding of solid and liquid water behavior.
The team incorporated
cooperativity with two additional parameters: the cooperativity coefficients A and B that capture influence of an infection with A on the subsequent infection with B, and vice versa.
This «
cooperativity,» discovered by Coryell and Pauling in 1939, is extremely important for hemoglobin's function in the body.
But A Way Out differs hugely from other games» co-op modes in that it takes
its cooperativity to the next level.