Asf1 act as a freight train that transports histones to the nuclei of our cells where the DNA is
copied during cell divisions.
Not exact matches
Here's what they found —
during cell division, UHRF1 recognizes newly
copied DNA at sites that are missing methyl tags.
This group also clarified that Shugoshin controls DNA replication (the process by which DNA makes a
copy of itself
during cell division) in subtelomeres as well as higher - order structure of chromosomes.
The shortening of telomeres is a process that occurs naturally in the body each time that a
cell divides:
during cell division the DNA, which is tightly packaged into chromosomes, must be duplicated but the DNA -
copying machinery design itself, prevents the full replication of the ends of the chromosomes.
«While these macromolecules are important for the parent
cell, they pose hindrances during cell division to segregating the copied chromosomes to daughter cells properly,» said Dr. Norihiko Nakazawa, of OIST's G0 Cell Unit, the paper's first aut
cell, they pose hindrances
during cell division to segregating the copied chromosomes to daughter cells properly,» said Dr. Norihiko Nakazawa, of OIST's G0 Cell Unit, the paper's first aut
cell division to segregating the
copied chromosomes to daughter
cells properly,» said Dr. Norihiko Nakazawa, of OIST's G0
Cell Unit, the paper's first aut
Cell Unit, the paper's first author.
Mutations can be caused by
copying errors in the genetic material
during cell division and by exposure to radiation, chemicals, or viruses, or can occur deliberately under cellular control
during the processes such as meiosis or hypermutation.
Researchers think they arise from occasional mistakes
during cell division, when DNA is jumbled up and
copied.
By controlling the transport of histones to our DNA, TLK and Asf1 ensure that the chromatin architecture and its information are
copied correctly
during cell division, so that
cell identity is maintained,» explains Ilnaz Klimovskaia.
During cell division, also known as mitosis, the entire DNA content of the
cell is
copied, with half going to each new
cell.