Tanaka had sequenced the middle region of the code for NS5B, the enzyme that makes new genome
copies during replication.
Not exact matches
This group also clarified that Shugoshin controls DNA
replication (the process by which DNA makes a
copy of itself
during cell division) in subtelomeres as well as higher - order structure of chromosomes.
The shortening of telomeres is a process that occurs naturally in the body each time that a cell divides:
during cell division the DNA, which is tightly packaged into chromosomes, must be duplicated but the DNA -
copying machinery design itself, prevents the full
replication of the ends of the chromosomes.
Moreover, given that point mutations are acquired through DNA
copy - errors (and / or failure of DNA damage repair mechanisms)
during replication, preferentially within the paternal germline, a detailed knowledge of these basic biological processes is key to understanding the patterns of nucleotide substitutions.
Nucleosomes are disassembled and reassembled
during DNA
replication to ensure a faithful
copy on each daughter strand.