Sentences with phrase «copies of a given gene»

Loss - of - function mutations can disrupt both copies of a given gene in humans and phenotypic analysis of such «human knockouts» can provide insight into gene function.

Not exact matches

To coax the apples to create these particular anti-browning RNA molecules, the scientists gave the apple extra copies of the browning gene that were tweaked to set off the plant's interference mechanism.
Chen and his colleagues, postdocs Xiongyi Huang, Jennifer Kan, and graduate student Ruijie Zhang, did this by giving the bacteria a copy of a gene that encodes an enzyme called cytochrome P450.
Giving multiple copies of the gene to addicts would prevent them...
In a now - famous report, petunias turned white when given extra copies of coloring genes.
Having only one variant copy of the gene gives people the appearance of looking about one year older on average, the team of Dutch and British researchers concluded.
Doctors gave the patients stem cells containing copies of a properly functioning gene for the enzyme; the babies» immune systems were then able to reconstitute themselves.
A large body of research has reported that Nanog is allelically regulated — that is, only one copy of the gene is expressed at any given time — and fluctuations in its expression are responsible for the differences seen in individual embryonic stem (ES) cells» predilection to differentiate into more specialized cells.
Lead researchers Eric Reiman and Pierre Tariot of the Banner Alzheimer's Institute in Phoenix plan to give a yet - to - be identified anti-amyloid drug, or placebo, to 650 people who carry two copies of the APOE4 gene — a genetic double whammy that confers a 10-fold increased risk of developing Alzheimer's late in life.
They also gave the cells a correct copy of the A1At gene so that the cell's DNA repair machinery would use it as a template to heal the break.
The study for the first time estimates the minimum number of locations in the human genome — 250 to 300 — where gene copy number variation (CNV) can give rise to autism spectrum disorder (ASD).
In this way, the mutation is somewhat similar to sickle cell anemia in humans, where having one copy of a mutated gene gives one an immunity to malaria, while two copies causes a painful, life - threatening illness.
«If a patient has a mutation in a specific gene, it would be a way of giving them a normal copy to try to correct that gene.
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