Sentences with phrase «copy number data»

Joey then followed up with an analysis of DNA copy number data derived from the same primary melanoma tumours.

SNP & Variation Suite offers a complete set of tools for processing raw intensity data, identifying regions of copy number variation (CNV), visualizing copy number data, and performing association analyses on a variety of copy number covariates.

Members of the TCGA Research Network identified and characterized four glioblastoma subtypes using gene expression, somatic mutation, and copy number data.

It's very similar to array - based copy number data, and amenable to the same segmentation methods.

Copy number data is dated 27 - May - 2014, and mutational data is dated 15 - Aug - 2017.

Not exact matches

In a new study published in The Quarterly Review of Biology, Dr. Karen Hardy and her team bring together archaeological, anthropological, genetic, physiological and anatomical data to argue that carbohydrate consumption, particularly in the form of starch, was critical for the accelerated expansion of the human brain over the last million years, and coevolved both with copy number variation of the salivary amylase genes and controlled fire use for cooking.

Using clinical, genetic, and gene expression data as filters to distinguish genes whose copy number alteration causes cancer from those for whom copy number changes are incidental, the team whittled down their list from 14,000 to a more manageable number, each of which they systematically tested using genetic experiments in animals.

«Our preliminary data in cancers such as prostate, colon, liver and lung suggest a punctuated model of copy number evolution is also likely to be operative in other solid cancers,» said Navin.

The authors next took 997 tumors in the discovery set, integrated copy number and gene expression data, and performed clustering analyses to identify subgroups of tumors with distinct features and clinical outcomes.

These new data suggest that transcriptome analysis can be used as a tool to predict the protein copy numbers per cell.

These datasets include: the actual genome sequences of the 1,011 isolates; the list of 4,940 common «core» ORFs plus 2,856 ORFs that are variable within the population (together these make up the «pangenome»); copy number variation (CNV) data; phenotyping data for 36 conditions; SNPs and indels relative to the S288C genome; and much more.

The software, called DECoN, accurately and quickly detects changes in copy number of blocks of DNA called exons, by analysing sequencing data already generated to identify smaller gene changes.

Anecdotal data on an increasing number of genes support this view: Drosophila has one copy each of the Ras, Raf and Notch genes, as well as of the genes of the Hox cluster, while vertebrates have three or more of each of these genes.

Using DECoN (which stands for Detection of Exon Copy Number variants), the researchers took advantage of the high density of sequencing data available in new gene panels to accurately detect deletions or duplications of exons.

Thus, we apply circular binary segmentation (CBS) to smooth the data and detect significant copy number change - points.

We aim to push its limits on all fronts to establish a technique which combines nanometre 3D resolution with maximum labelling efficiencies, absolute measurements of protein copy numbers, precise multi-colour measurements, high - throughput for large scale statistics and novel data analysis approaches, to address the vast array of exciting biological questions at the nanoscale, which are becoming accessible only now.

Copy the date into a spreadsheet, then divide the production by the number of employees and you get «tons - per - miner» for each year, once you've collected the data for each year.

There's also a lot of work under way for TCGA, not just the 6K capture project, but also adjunct analyses of gene expression, DNA copy number, microRNA, and DNA methylation data being generated on TCGA samples.

The sequence data easily can be used to identify single nucleotide deletion, insertion, polymorphism and translocation and copy a number of changes on the DNA level.

Methods: Sixty - eight parasites isolates with in vivo clearance data were obtained from two Tracking Resistance to Artemisinin Collaboration study sites in Cambodia, culture - adapted, and genotyped for pfkelch13 and other mutations including pfmdr1 copy number; and the RSA0 - 3h survival rates and response to antimalarial drugs in vitro were measured for 36 of these isolates.

By analyzing genome sequence data from human populations, including 1269 individuals from sub-Saharan Africa, we identify a diverse array of large copy number variants affecting the host invasion receptor genes GYPA and GYPB We find that a nearby association with severe malaria is explained by a complex structural rearrangement involving the loss of GYPB and gain of two GYPB - A hybrid genes, which encode a serologically distinct blood group antigen known as Dantu.

Results: We validate our approach using data with known copy number, identifying the vast majority of aneuploidies with a low rate of false discovery.

33/4: 00 A method for detecting intragenic copy number changes of BRCA1 and BRCA2 using next - generation sequencing data.

He led the Broad Institute's effort to analyze somatic DNA copy number alterations for The Cancer Genome Atlas (TCGA) and is now co-principal investigator of the Broad Institute's copy number Genome Data Analysis Center for the National Cancer Institute's Genomic Data Analysis Network (GDAN).

INCLUDES: 36 Student Activity Books (1 copy of each of the six titles per grade level, 32 - pages each) 4 Answer Cases 1 Teacher Guide FEATURES: Flexibility for task centers, independent or partner work, or one - on - one tutoring / remediation Clearly stated objective for each activity that allows you to differentiate Focus on foundational skills and concepts Engaging puzzle format for a fun challenge Immediate feedback for self - checking Titles: Grade 1: Number and Operations: Counting and Place Value Addition and Subtraction: Properties and Situations Addition and Subtraction: Strategies and Equations Addition and Subtraction: Beyond 20 Measurement and Data: Length, Time, and Analysis Geometry: Shapes and Attributes Grade 2: Addition and Subtraction: To 20 and Beyond Foundations of Multiplication: Equal Groups and Arrays Addition and Subtraction: Properties and Place Value Measurement and Data: Length, Time, and Analysis Measurement and Data: Time, Money, and Analysis Geometry: Shapes and Attributes Grade 3: Number and Operations: Multiply and Divide Multiply and Divide: Problem Solving Fractions: Fractions as Numbers Measurement and Data: Use and Interpret Data Geometric Measurement: Perimeter and Area Geometry: Shapes and Attributes Grade 4: Number and Operations: Whole Numbers Number and Operations Multi-Digit and Fractions Fractions: Equivalence and Ordering Fractions: Operations Measurement and Data: Convert and Solve Problems Geometry: Angles and Plane Figures Grade 5: Operations and Algebraic Thinking: Expressions and Patterns Number and Operations: Whole Numbers and Decimals Fractions: Add and Subtract Measurement and Data: Convert and Interpret Geometric Measurement: Volume Geometry: Graphing and 2 - D Figures Grade 6: Ratio and Proportions: Ratios and Problem Solving The Number System: Rational Numbers The Number System: Factors and Multiples Expressions and Equations: Write, Solve, and Analyze Geometry: Problem Solving Statistics and Probability: Variability and Displays

INCLUDES: 6 Student Activity Books (1 copy of each title, 32 - pages each) 2 Answer Cases 1 Teacher Guide FEATURES: Flexibility for task centers, independent or partner work, or one - on - one tutoring / remediation Clearly stated objective for each activity that allows you to differentiate Focus on foundational skills and concepts Engaging puzzle format for a fun challenge Immediate feedback for self - checking Level 4 Titles: Number and Operations: Whole Numbers Number and Operations Multi-Digit and Fractions Fractions: Equivalence and Ordering Fractions: Operations Measurement and Data: Convert and Solve Problems Geometry: Angles and Plane Figures

INCLUDES: 24 Student Activity Books (4 copies of each title, 32 - pages each) 8 Answer Cases 1 Teacher Guide FEATURES: Flexibility for whole - class practice, small - group guided practice, independent or partner work, learning stations Clearly stated objective for each activity that allow you to differentiate Focus on foundational skills and concepts Engaging puzzle format for a fun challenge Immediate feedback for self - checking Level 5 Titles: Operations and Algebraic Thinking: Expressions and Patterns Number and Operations: Whole Numbers and Decimals Fractions: Add and Subtract Measurement and Data: Convert and Interpret Geometric Measurement: Volume Geometry: Graphing and 2 - D Figures

INCLUDES: 24 Student Activity Books (4 copies of each title, 32 - pages each) 8 Answer Cases 1 Teacher Guide FEATURES: Flexibility for whole - class practice, small - group guided practice, independent or partner work, learning stations Clearly stated objective for each activity that allow you to differentiate Focus on foundational skills and concepts Engaging puzzle format for a fun challenge Immediate feedback for self - checking Level 4 Titles: Number and Operations: Whole Numbers Number and Operations Multi-Digit and Fractions Fractions: Equivalence and Ordering Fractions: Operations Measurement and Data: Convert and Solve Problems Geometry: Angles and Plane Figures

INCLUDES: 6 Student Activity Books (1 copy of each title, 32 - pages each) 2 Answer Cases 1 Teacher Guide FEATURES: Flexibility for task centers, independent or partner work, or one - on - one tutoring / remediation Clearly stated objective for each activity that allows you to differentiate Focus on foundational skills and concepts Engaging puzzle format for a fun challenge Immediate feedback for self - checking Level 1 Titles: Number and Operations: Counting and Place Value Addition and Subtraction: Properties and Situations Addition and Subtraction: Strategies and Equations Addition and Subtraction: Beyond 20 Measurement and Data: Length, Time, and Analysis Geometry: Shapes and Attributes

INCLUDES: 6 Student Activity Books (1 copy of each title, 32 - pages each) 2 Answer Cases 1 Teacher Guide FEATURES: Flexibility for task centers, independent or partner work, or one - on - one tutoring / remediation Clearly stated objective for each activity that allows you to differentiate Focus on foundational skills and concepts Engaging puzzle format for a fun challenge Immediate feedback for self - checking Level 5 Titles: Operations and Algebraic Thinking: Expressions and Patterns Number and Operations: Whole Numbers and Decimals Fractions: Add and Subtract Measurement and Data: Convert and Interpret Geometric Measurement: Volume Geometry: Graphing and 2 - D Figures

INCLUDES: 24 Student Activity Books (4 copies of each title, 32 - pages each) 8 Answer Cases 1 Teacher Guide FEATURES: Flexibility for whole - class practice, small - group guided practice, independent or partner work, learning stations Clearly stated objective for each activity that allow you to differentiate Focus on foundational skills and concepts Engaging puzzle format for a fun challenge Immediate feedback for self - checking Level 3 Titles: Number and Operations: Multiply and Divide Multiply and Divide: Problem Solving Fractions: Fractions as Numbers Measurement and Data: Use and Interpret Data Geometric Measurement: Perimeter and Area Geometry: Shapes and Attributes

Incredible original condition Just in from Southern California Rare European model — sold new in Sweden 47,940 actual miles (77,152 KM) Matching numbers original engine Beautiful, factory correct paintwork Wonderfully original interior Over $ 27,000 spent on recent service work completed by a marque specialist that included complete brake, cooling, exhaust, fuel injection system rebuilds and more Documentation includes factory books, radio books, service records, $ 27,000 in recent service receipts, copy of build data card, factory tools and more Options include: New whitewall tires Becker Europa radio Rare 4 - speed manual transmission Drives and performs incredibly well!

The number of copies in stock is drawn from Amazon's own data, and is not reported anywhere else on the Web.

A number of companies currently offer digitization services that operate well within the law; companies can digitize their back data for storage, and readers can order ebook copies of out - of - print and rare editions.

As far as total numbers of copies sold, that data will not be included at the present time in Nielson's information, only the ranking of the books in order.

The service draws on Amazon's vast database of past sales data and analyzes the relationship between price changes and number of copies sold.

The Digital Reader has reported that KDP is now offering data on price points for ebooks: «The service draws on Amazon's vast database of past sales data and analyzes the relationship between price changes and number of copies sold.

No review is published until SLJ has received two copies of the book and the following bibliographic information: author, title, binding (s), price (s), publication month and year, ISBN (s), Library of Congress number (or notice that there will not be one) and whether or not Cataloging in Publication data will appear in the book.

The way I run these screens is to copy and paste the CCC list into excel, add the functions / formulas for my screens, then sort all of the data by the final ranking number (this is the excel sheet I can send you).

There are a number of viable cloud solutions for backups that will enable you to maintain an off - site copy of your data.

According to numbers collected by the Game Data Library, Splatoon 2 has sold over one million copies in Japan alone, accounting for one in every three Switch games sold in the country.

You agree not to engage in any of the following prohibited activities: (i) copying, distributing, or disclosing any part of the Service in any medium, including without limitation by any automated or non-automated «scraping»; (ii) using any automated system, including without limitation «robots,» «spiders,» «offline readers,» etc., to access the Service in a manner that sends more request messages to the Company servers than a human can reasonably produce in the same period of time by using a conventional on - line web browser (except that Humble Bundle grants the operators of public search engines revocable permission to use spiders to copy materials from Humble Bundle for the sole purpose of and solely to the extent necessary for creating publicly available searchable indices of the materials, but not caches or archives of such materials); (iii) transmitting spam, chain letters, or other unsolicited email; (iv) attempting to interfere with, compromise the system integrity or security or decipher any transmissions to or from the servers running the Service; (v) taking any action that imposes, or may impose in our sole judgment an unreasonable or disproportionately large load on our infrastructure; (vi) uploading invalid data, viruses, worms, or other software agents through the Service; (vii) collecting or harvesting any personally identifiable information, including account names, from the Service; (viii) using the Service for any commercial solicitation purposes; (ix) impersonating another person or otherwise misrepresenting your affiliation with a person or entity, conducting fraud, hiding or attempting to hide your identity; (x) interfering with the proper working of the Service; (xi) accessing any content on the Service through any technology or means other than those provided or authorized by the Service; (xii) bypassing the measures we may use to prevent or restrict access to the Service, including without limitation features that prevent or restrict use or copying of any content or enforce limitations on use of the Service or the content therein; (xiii) sell, assign, rent, lease, act as a service bureau, or grant rights in the Products, including, without limitation, through sublicense, to any other entity without the prior written consent of such Products» (defined below) licensors; (xiv) circumventing Service limitations on the number of Products you may purchase, including, without limitation, creating multiple accounts and purchasing a total number of Products through such multiple accounts which exceed the per - user limitations; or (xv) except as otherwise specifically set forth in a licensor's end user license agreement, as otherwise agreed upon by a licensor in writing or as otherwise allowed under applicable law, distributing, transmitting, copying (other than re-installing software or files previously purchased by you through the Service on computers, mobile or tablet devices owned by you, or creating backup copies of such software or files for your own personal use) or otherwise exploiting the Products (defined below) in any manner other than for your own private, non-commercial, personal use.

But if Latimer Alder is claiming that control of data is so unimportant, that the number of copies of data is not taken seriously, that no one has been ever exposed to discipline or criminal charge for violating the security of data through mishandling of backups, then he is flat - out making false claims.

Any less, or more, than the business - justified number of copies violates the principles of data security.

Using forensic methodologies, it is possible to identify what was taken, when it was copied, by whom and even the manufacturer and serial number of the exact device the data was copied onto, thus providing concrete computer forensic evidence for court if needed.

We don't usually)-- fields of data: date, open price, high, low, closing, and volume — we are now sometimes asked for «number of trades» and I do not see that included — data opens up in an Excel spreadsheet; I was able to easily copy and paste it over into my office version of Excel — I did not see the ability to pull up summaries of weekly, monthly, quarterly, or yearly data (Canada Stockwatch doesn't offer this either).

Response: Based on information and data received in the public comments, the estimate for the number of people requesting inspection and copying has been revised.

There are a number of viable cloud solutions for backups that will enable you to maintain an off - site copy of your data.

Wylie, however, noted that it was difficult to verify the exact number since data was a «fungible thing» and once it left your system and your database, one could make as many copies as possible.

In advance of Weiss Ratings publishing the data, a number of purportedly leaked copies surfaced on the web.