Sentences with phrase «copy number effect»
However, such CRISPR screens are sensitive to a phenomenon called the copy number effect, where genes that have been repeatedly duplicated within a cell (as commonly happens in cancer cells) can be flagged as essential regardless of whether they are or not.
https://www.broadinstitute.org/ Not exact matches
With its large sample size, this study had the power to find copy number variants with large effects that occur in more than 0.1 percent of schizophrenia cases.
The largest numbers of variants identified by genome - wide association are copy - number changes, which have a greater phenotypic effect than do single nucleotide polymorphisms.
The degree of phenotypic correction of murine ß — thalassemia intermedia following lentiviral - mediated transfer of a human γ — globin gene is influenced by chromosomal position effects and vector copy number.
In support of this threshold effect, doubling or tripling peel - 1 copy number among male - sired embryos did not produce a more severe phenotype, at least as measured by the onset of epidermal leakage (Figure 5D).
In effect, both agreements accomplish the same level of restriction, but you have a little more leeway with the number of copies with the Sony Reader.
All new copies of the game will include a VIP code — much like the code that activated the Cerberus Network for Mass Effect 2 — which will give access to a number of new multiplayer maps on day one.
The PlayStation 3 version of Mass Effect 3 debuted at number 20 on the weekly Japanese sales chart, shifting just over 8000 copies.
@Philipp Per - CPU is quite common for business and enterprise software, and has the amusing side - effect that allows any number of copies to be made provided that the number in use at any one time doesn't exceed the number permitted by the license (unless of course the licenses are tied to specific CPU serial numbers).
Since you are not limited by formatting and the actual hard copy pages of your resume, you may be carried away to use effects and graphics along with a number of your personal details that are not relevant.