Sentences with phrase «copy number gains»

31) Soh J, Okumura N, Lockwood WW, Yamamoto H, Shigematsu H, Zhang W, Chari R, Shames D, Tang X, MacAulay C, Varella - Garcia M, Vooder T, Wistuba II, Lam S, Brekken R, Toyooka S, Minna JD, Lam WL, Gazdar AF (2009) Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells.

Median progression - free survival for the 13 patients who had a decrease in the number of CTCs with ALK copy number gain was 14.0 months, while the median progression - free survival for the 16 patients who had stable or increased numbers of CTCs with ALK copy number gain was 6.1 months.

All patients had both CTCs with ALK rearrangements and CTCs with ALK copy number gain before treatment and at two months.

Analysis of CTC numbers at the different time points showed that the one measurement that was statistically significantly associated with progression - free survival was a change in the number of CTCs with ALK copy number gain over time.

Not exact matches

In this rare phenomenon, the copy number variants are predominantly gains — duplications and triplications — rather than losses of genetic material, and are present in all the cells of the child.

Using a variety of techniques, the researchers scanned the genetic material for so - called copy number variants, in which relatively long stretches of DNA are lost or gained.

The resulting DNA copy number variation and patterns of chromosome loss and gain are tumor - type specific, suggesting differential selective pressures on the two tumor cell types.

By analyzing genome sequence data from human populations, including 1269 individuals from sub-Saharan Africa, we identify a diverse array of large copy number variants affecting the host invasion receptor genes GYPA and GYPB We find that a nearby association with severe malaria is explained by a complex structural rearrangement involving the loss of GYPB and gain of two GYPB - A hybrid genes, which encode a serologically distinct blood group antigen known as Dantu.

Given those facts, then it's safe to argue that if some young woman named Nicole Polizzi had written the same books before gaining her celebrity status as Snooki, her first book wouldn't have even have sold 0.1 % of the number of copies it has sold to date.

In this video, author Chris Fox talks about giving away a significant number of review copies to gain a spot in the top 20 in the Audible category.

Binary Options Social / Copy trading is very much in it's infancy, and it is still not clear how Binary Option brokerages would deal with the risks involved in having a huge number of traders enter into the similar positions should any Signal Providers gain a significant amount of notoriety.