Sentences with phrase «copy of an allele»

Kwon adds that many, but not all, controllers show an enriched presence of multiple copies of these alleles.

The downside is that someone with two copies of the allele suffers from sickle - cell anemia, an incurable blood disorder.

The linear subtype is propelled by just two driver events: a genetic condition called von Hippel - Lindau syndrome, and loss of one copy of an allele in chromosome 3.

The genetic variant identified to be associated with the brain aging rate at the TMEM106B locus is also extremely frequent: 80 percent of the population carries at least one copy of the allele associated with increased aging rate in their genome, Rhinn said.

Dogs frequently will have two copies of an allele that is identical for a trait.

Any dog that has at least one copy of his allele and does not have a copy of the most dominant allele will have yellow hair with a darker mask on the face.

Not exact matches

I have two copies of the slow metabolism allele, which means I have an efficient metabolism: My body does a good job of storing food as energy so, unlike some, I don't need to eat just before I work out in order to have enough energy to work out.

During reproduction, humans inherit two working copies of most genes — one copy, or allele, from each parent.

Because there's only one functioning allele of an imprinted gene, if that copy becomes defective, developmental abnormalities can occur.

Taking advantage of the handful of complete human genome sequences now available, the pair looked at how alleles — the two copies of each gene we inherit from our parents — differ within a genome.

In the U.S., this behavioral division follows a genetic one: workers bearing two copies of one form, or allele, of the Gp - 9 gene live in nests governed by a single matriarch, whereas those that have one copy or a pair of a second allele take orders from a female oligarchy.

Again, the increased activity in these areas was associated with the number of copies of the A allele carried by individuals — people with two copies showed a larger increase in activity than those with just one.

The team looked for patterns associated with two COLIA1 alleles, called S and s. Women who had one copy of the s allele had bone density in the thighbone and lower spine that was 2 % less than that of women with no s alleles.

Those carrying two copies of the other variant — the G allele — remembered the least, with the performance of those carrying one copy of each variant lying somewhere in the middle.

Women with two copies of s fared even worse: They had bones that were 4 % less dense — and faced a 280 % higher risk of fracture — than did women without any s alleles, says team member Andre Uitterlinden, a molecular geneticist at Erasmus University in Rotterdam, the Netherlands.

Participants carrying two copies of one variant within the PRKCA gene, dubbed the A allele, remembered the most details about the pictures.

For example, they revealed that most organisms have two copies of each gene, one from each parent, and that a gene comes in a variety of different forms, or alleles.

Everyone has two copies, or alleles, of the 2A receptor gene, one from each parent.

Genetic tests revealed that all ants in a monogyne colony have two copies of the B allele, but among the polygynes, at least 10 % are heterozygous, carrying a mutant allele, b, which Krieger says appears to code for a faulty protein.

A forward genetic screen in Drosophila melanogaster (fruit flies) identified mutant copies, or alleles, of a gene called cacophony associated with defects in autophagy and cellular homeostasis.

Every person has two copies, or alleles, of each gene, inheriting one copy from each parent.

Center for Elephant Conservation, elephants have 38 additional modified copies (alleles) of a gene that encodes p53, a well - defined tumor suppressor, as compared to humans, who have only two.

But Lo's team found more of the healthy allele, suggesting that the fetus had inherited the correct maternal copy of the gene and would not develop beta - thalassaemia.

For the particular variant of interest, one version, the T allele is more common, and of 196 patients, 135 had two copies of the T allele.

Of the remaining 61 patients, 54 had one copy of T allele and one copy of the minor G allele, and 7 patients had two copies of the G allelOf the remaining 61 patients, 54 had one copy of T allele and one copy of the minor G allele, and 7 patients had two copies of the G allelof T allele and one copy of the minor G allele, and 7 patients had two copies of the G allelof the minor G allele, and 7 patients had two copies of the G allelof the G allele.

A child of parents who each possess one copy of the sickle - cell trait has a one - in - four chance of inheriting both sickle - cell alleles — and thus getting sickle - cell anemia.

Their work, which is published in Nature Ecology and Evolution, shows for the first time the existence in Leishmania of a relation between changes in chromosome copy number and the selection of new alleles important for parasite survival.

At least one allele (or copy of the gene) is carried by 80 percent of some South American populations.

The queen bee, who, in the course of their mating flight, mate with different drones multiple times, passes on to fertilized eggs a random combinations of two csd copies, so - called alleles.

In 15 of the brain samples, researchers found that one copy of DRD2 was producing at least 50 percent more mRNA than the other one; in the remaining brains, they discovered that both alleles produced equal amounts.

Researchers were specifically hunting for the mRNA created from the two alleles (copies) of the gene DRD2, which codes for a receptor protein for the neurotransmitter dopamine.

Horses homozygous (having two copies) of one version (allele) of the gene — the so - called CC horses — are sprinters, she says.

For these 3 SNPs, we report the ORs for use of aspirin, NSAIDs, or both across genotypes corresponding to 0, 1, or 2 copies of the variant allele (eTable 5 in the Supplement) and the ORs for each SNP by strata of use of aspirin, NSAIDs, or both with 1 common reference group (eTable 6 in the Supplement), to fully describe the interaction.

A mitochondrial heteroplasmy occurs when an individual carries copies of mtDNA with different alleles.

All people have two copies of every gene, and earlier work by the researchers on identical twins with leukemia indicates that a second genetic alteration - involving the second copy of the TEL gene, one of the two so - called «alleles» — occurs post-natally to actually nudge blood cells into a leukemic state.

This small group of genes are expressed and functional only from a copy inherited from only from our mother or only from the father, in contrast to the over 20,000 genes expressed from alleles inherited from both parents.

From these data, we first measured allele - specific expression, where a heterozygous site in a gene can be used to distinguish gene expression from the two copies of a gene.

Allele - specificity: ensuring that only the mutant copy of the HD gene, and not the healthy one, is removed.

Between 3 - 8 % of people of European descent carry one copy of the factor V Leiden allele and 1 in 5,000 people have two copies.

In tumor samples, where we frequently encounter variants with a very small allele frequency due to contamination with normal tissue, copy number variation, and tumor heterogeneity, high coverage is essential for accurate detection of these variants with high power.

After three days, they tested each cell in every embryo to learn how many had two copies of the wild - type allele.

Another group at increased CVD risk are those with one or two copies of the apoE4 allele (gene).

A dilute phenotype requires two copies of the recessive d allele.

Dogs need at least one copy of the «T» allele to have a wavy or curly coat; the ancestral «C» allele is associated with a straight coat.

Dogs with at least one copy of the T allele have about a 50 % of chance of having hind dewclaws.

Mesocephalic (Staffordshire Terrier, Labrador) and dolichocephalic (Whippet, Collie) dogs have one, or more commonly two, copies of the ancestral C allele.

The dog has two copies of the recessive «d» allele and will have a dilute colored coat.

The E-Allele test determines how many copies of the recessive «e» alleles a dog carries.

The Em - Allele test determines how many copies of the melanistic mask allele a dog caAllele test determines how many copies of the melanistic mask allele a dog caallele a dog carries.

This mutation is recessive so two copies of the mutated gene (or «d» allele) are needed to produce the dilute coat color.