«MHCI levels are altered in the Alzheimer's brain, and altering MHCI levels in mice disrupts memory, reduces synapse number and causes neuronal insulin resistance, all
of which are
core features of Alzheimer's
disease,» Boulanger said.
Dr. Collingridge's recent research suggests improperly regulated LTD could cause the degeneration
of the connections between neurons that is a
core feature of Alzheimer's and other neurodegenerative
diseases.