Not exact matches
In this way the binding of the DNA to the
corresponding nucleosome is
changed so that the DNA for example becomes accessible for transcription enzymes and activates a particular
gene.
«We also found that reduced cohesin led to
changes in the expression of
genes involved
in nerve cell development and the response to an immune signaling protein,»
corresponding author Toshihide Yamashita says.
Results: Within 4 h, activation of CD4 (+) T cells invokes
changes in histone modifications and enhancer RNA transcription that
correspond to altered expression of the interacting
genes identified by promoter capture Hi - C.
Changes in chromosome copy numbers were correlated with the
corresponding transcript levels, but additional aneuploidy - independent regulation of
gene expression was observed.