First described in the 1990s — a discovery that led to the 2006 Nobel Prize — RNAi is a process by which organisms suppress the expression of target genes through the action of small RNA segments that bind to
corresponding gene sequences.
Not exact matches
Then, using the CRISPR - Cas
gene - editing tool, they spliced
sequences corresponding to individual video pixels into the genome.
Since messenger RNA is nothing but the imprint of the
gene whose message it is carrying, it is possible to use it to chemically generate the DNA
sequence or
gene it
corresponds to.
Molecules of dsRNA are known to travel between body cells (any cell in the body except germ cells, which make egg or sperm cells) and can silence
genes when their
sequence matches up with the
corresponding section of a cell's DNA.
Both studies relied on a popular lab organism known as C. elegans, a nearly microscopic nematode that is fast growing, translucent and has a
sequenced genome showing that nearly half its
genes are closely related to
corresponding human
genes.
In this way the team could create a composite image representing the
sequence, and location, of RNA
corresponding to every
gene in the human genome.
Because
genes on the Y chromosome often vary slightly in
sequence — and even function — from the
corresponding genes on the X, males could have slightly different patterns of
gene expression throughout the body compared with females, due to not only their hormone levels, but also their entire Y chromosome.
Double - stranded RNA can silence the expression of a
gene with a
corresponding sequence, a process called RNA interference (RNAi).
Our cells read the
sequence of chemical letters in DNA to make proteins, and the DNA
corresponding to one protein is called a
gene.
A Golden Gate TALEN kit (Addgene) was used to generate two sets of RVD plasmids
corresponding to the
sequences found in the first coding exon of the CCHa2 - R
gene (1L, 1R, 2L, and 2R; S2 Fig).
Using exome
sequences from 3222 British - Pakistani individuals with high parental relatedness, we estimate a mutation rate of 1.45 ± 0.05 × 10 -LRB--8) per base pair per generation in autosomal coding
sequence, with a
corresponding non-crossover
gene conversion rate of 8.75 ± 0.05 × 10 -LRB--6) per base pair per generation.
Gene a region of genomic DNA
sequence,
corresponding to a unit of inheritance.
The DNA dart had found its
corresponding sequence in the vast tangle of chromosomal DNA; he'd targeted a specific
gene.