Sentences with phrase «costimulatory receptors»

Newly - discovered mechanism of action of the bacterial superantigen toxins: Superantigens bind to both B7 - 2 and CD28, the major costimulatory receptors expressed on human immune cells.

Insight into this mechanism led the researchers to design new peptides — snippets of the human B7 - 2 receptor protein — that powerfully block the binding of a superantigen to its costimulatory receptor targets, and thereby protect against lethal toxic shock, as they showed in animals.

Not exact matches

Involved in the costimulatory signal essential for T - cell receptor (TCR)- mediated T - cell activation.