Given these results, the utility of the CBCL as a screening device can only be defended if the benefit of detecting a minority of cases offsets the costs of the screen coupled with
the costs of false positives.
Is it possible to decrease
the costs of false positives?
Not exact matches
The national
cost of false -
positive tests and overdiagnosed breast cancer is estimated at $ 4 billion a year, according to a 2015 study in Health Affairs.
Specifically, the task force says the «harms and
costs of false -
positive results, over diagnosis and overtreatment» outweigh any «significant reductions in the relative risk
of death from breast cancer.»
But
cost - benefit decisions, even as the price
of Tc - 99m rises when supply shrinks, should include the
cost of follow - up tests after a
false -
positive thallium scan, he urges.
It rarely detects important disease and does not reduce mortality and is associated with discomfort for many women,
false positive and negative examinations, and extra
cost,» said Dr. Linda Humphrey, a co-author
of the guideline and a member
of ACP's Clinical Practice Guidelines Committee.
Inappropriate testing for heart attacks increases the
cost of treatment; increases the number
of false positives, which could lead to further testing and unnecessary consultations; and adds to patient anxiety, said Dr. Anil Makam, Assistant Professor
of Internal Medicine at UT Southwestern and first author
of the study published today in JAMA Internal Medicine.
«Our method would be an effective low -
cost addition to a battery
of tests helping to lower the
false positive rate since it provides 10 % better sensitivity and specificity than any other screening method, including Pap and HPV tests,» says Huang.
«Facets
of costs should be incorporated in evaluation, when available, as
false negatives might be more costly than
false positives, for example.
The
cost of testing (and often re-testing because
of false positive test results) could possibly hinder the success
of a spay and neuter program.
But using this tends to blind decision - makers to the
costs of acting on
false positives: exaggerated warnings or even
false alarms.
In its enthusiasm to adopt innovative statistics - based solutions, the industry may be in danger
of undermining the progress made in predictive maintenance to date, by driving an increase in «
false positives» that, in turn, will result in increased Opex
costs for operators.
Mostly I worry that consumers won't stop to consider the choice
of success metrics, let alone question the defaults and the priorities they express.14 As we've found, accuracy isn't always the right metric, and there are real
costs associated with
false positives.
Only Trend Micro did better overall, zapping all
of the zero - days, but at the
cost of eight
false positives; the industry average was six.