The volume of the cerebellum is expressed as a percentage of the caudal
cranial fossa volume (Panels A and B: Cerebellar CCF Percentage) and a percentage of the total brain volume (Panels C and D: Cerebellar Brain Percentage).
It is possible that this reflects increased height of the rostral part of the caudal
cranial fossa (pars rostralis).
A more acute Angle 2 could result from a short basicranial axis in the caudal
cranial fossa and (even more) premature fusion of the spheno - occipital synchondrosis.
The bony changes characteristic for CM are shortening (craniosynostosis) of the basicranium and supraoccipital bone resulting in an insufficient caudal
cranial fossa volume.
Earlier unpublished pilot studies had suggested that height of the rostral and caudal
cranial fossa may be an important variable.
Moreover, Cavalier King Charles spaniels have relatively increased cerebellar volume compared to other breeds and overcrowding of the cerebellum in the caudal part of the caudal
cranial fossa is correlated with the development of syringomyelia [6]--[9].
Crowding of cerebellum is defined as the percentage of the volume of each part of the caudal
cranial fossa (CCF) which is occupied by cerebellar parenchyma (panel A: Rostral Cerebellar CCF Percentage, panel B: Caudal Cerebellar CCF Percentage).
As with Classical Chiari type I malformation in humans, CKCS appear to have a shallower caudal
cranial fossa and have abnormalities of the supraoccipital and basioccipital bones when compared to mesaticephalic breeds (breeds with a skull of intermediate length and width)[16].
A more acute Angle 2 and longer Line AE with increased rostral
cranial fossa height (F - diameter) was also observed in dogs with syringomyelia but without CM e.g. Dog F (Figure 2).
Occipital dysplasia (i.e. widened foramen magnum) also may be seen [29]; however this is probably an acquired condition due to overcrowding of the caudal
cranial fossa, mechanical pressure from the cerebellum and supraoccipital bone resorption [30].
It has been found that pre-natal posterior
cranial fossa development in humans is independent of cerebellar volume but closely parallels the development of the supratentorial bony compartment [43].
Another difficulty is that for economic reasons, assessment of breeding dogs is made from only 3 MRI sequences of a limited anatomical area that does not include the entire
cranial fossa [32].
Crowding of cerebellum is defined as the percentage of the volume of each part of the caudal
cranial fossa (CCF) which is occupied by cerebellar parenchyma (Rostral Cerebellar CCF Percentage and Caudal Cerebellar CCF Percentage).
The center of the circle (F) was used as a vertex and the occipital circle could also be used as an assessment of the size of the caudal
cranial fossa by measuring the distance and angulation of the point where the circle bisected to the dorsal cerebellum (E).
A more acute Angle 5 was significant for both syringomyelia and CM and this finding suggests that these disorders in the dog are not just a consequence of a small volume caudal
cranial fossa but shortening of the entire cranial base.
Not exact matches
The morphometry of the skull has been examined in detail and the development of clinical signs and syringomyelia has been correlated to reduced caudal
fossa to
cranial cavity volume ratios and stenosis of the jugular foramen respectively.
Masks were recorded for the following volumes (mid-saggital view): Parenchyma within the
cranial cranial fossa (red), cerebellum (purple), brainstem (dark green), CCF (light green).
CCF,
cranial cranial fossa, and brain parenchyma volumes of all SB and LD individuals and 42 CKCS were used in a previous study [18].
The
cranial base is angled at the level of the hypophyseal
fossa where the rostral prechordal and caudal chordal parts meet.
CCF,
cranial cranial fossa and brain parenchyma volumes of 49 CKCS individuals were used in another study [19].