Sentences with phrase «create haploid cells»
The gonads (testicles and ovaries) divide the chromosomes to create haploid cells, namely spermatozoa and eggs.
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These resultant haploid cells can fuse with other haploid cells of the opposite sex or mating type during fertilization to create a new diploid cell, or zygote.
Here we used genome - saturated mutagenesis to create a biobank of over 100,000 individual haploid mouse embryonic stem (mES) cell lines targeting 16,970 genes with genetically barcoded, conditional and reversible mutations.