Sentences with phrase «create microfluidic»

Our goal is to create a microfluidic 3D cell culture system representing a «placenta - on - a-chip» in order to mimic the nutrient / waste transfer between maternal blood and fetal blood that occurs in the cotyledon section of the placenta, and to test and observe the effects of ethanol within the maternal bloodstream and compare it to a similar in vivo situation.
This novel nMIS sensor could be used to create microfluidic platforms that test for various diseases.
«Using a new layer - by - layer fabrication process, we created a microfluidic environment in which TEER - measuring electrodes are integral components of the chip architecture and are positioned as close as possible to the tissues grown in one or both of two parallel running channels,» said Olivier Henry, Ph.D., a Wyss Institute Staff Engineer who was the driving force behind the new Organ Chip designs.

Not exact matches

The researchers found that by tuning certain dimensions of the microfluidic lattice, they were able to direct billions of microbes to align and swim in the same direction, much the way electrons circulate in the same direction when they create a magnetic field.
By combining chip technology and microfluidics, Yang has created an inexpensive miniature microscope.
To apply the ink to the leaves, the researchers created a printing mold with a microfluidic channel.
With this method, they created a three - dimensional array of permeable carbon nanotubes within a microfluidic device, through which fluid can flow.
«The intimate skin interface created by this wearable, skin - like microfluidic system enables new measurement capabilities not possible with the kinds of absorbent pads and sponges currently used in sweat collection,» said John A. Rogers, who led the multi-institution research team that created the «lab on the skin.»
Both scientists are involved in the new IamFluidics spinoff, in which in - air microfluidics is used to create functional particles and materials.
«Thus, thanks to this unique program, we teamed up with McGill's bioengineers and microfluidic and mathematical modelling experts to create the device required for our study.»
They extracted cytoplasm from frog eggs, which contains dynein and all of the components needed to make spindles, added fluorescent protein and the chemotherapy drug Taxol to create and stabilize microtubules, and loaded the mixture into «the world's simplest microfluidic chamber.»
The technique could be useful could be useful in fabricating microfluidic devices, creating biomaterials that respond dynamically to stimuli and in patterning artificial tissue.
Here, we exploited microfluidics to control the metabolism of liver cells down to a resolution of a few cells, allowing us to create liver tissue that shows the same patterns of toxicity caused by differences in drug metabolism as the liver in your body.»
Khine uses Shrinky Dinks — a favorite childhood toy that shrinks when you bake it in the oven — to build microfluidic chips to create affordable tests for diseases in developing countries.
Creating organ models on a microscale has been greatly facilitated by microfluidics, a technology developed in the 1990s that uses micropumps, valves and finely etched channels to manipulate the movement of fluids through a chip.
Tiny test samples and the inability to experimentally reproduce aggregation events create further problems, but microfluidics addresses all of these issues.
Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed hydrogel based microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign
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