The imbalance
created by oxidative stress produces peroxides and free radicals, which contribute to a number of degenerative conditions, including aging.
Not exact matches
In Ames dwarrf, Snell Dwarf mice, Klotho mice, GHKO mice who have little IGF and GH; and live longer than wild - type; we see that indeed insulin and glucose / nutrient / energy pathways (which
create oxidative stress through excessive nutrient via elevated glycation blood glucose
creating high glycated albumin and hemoglobin), that aging is acted on
by IGF through hormones, GFs, GHs, acting on insulin signals, which act on survival genes (DAF / SIRT / FOXO).
«Energy deficits
created through both CR and EX reduce DNA and RNA damage to WBC, potentially
by reducing systemic
oxidative stress», the researchers conclude.
Remember, your body is continually bombarded every day
by free radicals (
creating oxidative stress) from exercise, air pollution, smoke, sun exposure, junk food, exposure to chemicals, etc..