The scientists first compared mouse megakaryocyte cells
created from embryonic stem cells engineered to lack p45 - Nfe2 with normal megakaryocytes.
Not exact matches
Scientists looking for new methods to make human tissue have successfully used cloning technology to
create embryonic stem cells from skin
cells.
A pluripotent state makes the resulting
cells indistinguishable
from embryonic stem cells, and the scientists got these
cells without
creating or destroying any embryos.
Eighteen adults with severe eye disease who were among the first people to receive transplants
created from human
embryonic stem cells (hESCs) continue to have no apparent complications with the introduced
cells after an average of nearly 2 years, according to the latest status report on their health.
This year, however, a report
from researchers at Children's Hospital Boston and the Harvard
Stem Cell Institute revealed that Hwang was indeed a pioneer — albeit by unwittingly exploiting an altogether different approach to creating embryonic stem ce
Stem Cell Institute revealed that Hwang was indeed a pioneer — albeit by unwittingly exploiting an altogether different approach to
creating embryonic stem ce
stem cells.
That breakthrough was one of a six - year chain of discoveries that included his 2007 work demonstrating the nuclear transfer method to
create embryonic stem cells from a nonhuman primate.
Of course, such
embryonic stem cells are not available in adult patients, so being able to
create them
from regular
cells is an important step.
The paper doesn't include any genetic analysis of the final eggs that confirms they are healthy, notes Mitinori Saitou, a
stem cell biologist at Kyoto University in Japan whose team developed methods to
create mouse egg
cells from embryonic or reprogrammed
stem cells.
Organlike tissue bits can be generated
from pluripotent
stem cells that are either plucked
from embryos or
created by taking a person's adult skin or blood
cells and chemically inducing them to revert to an
embryonic - like state.
Although
embryonic stem cells are naturally pluripotent, iPS
cells are
created by scientists
from existing adult
cells, such as skin or blood.
Last January, the House of Representatives voted, 253 to 174, to pass a bill, H.R. 3, that would allow researchers to use leftover embryos
from in vitro fertilization (IVF) clinics to
create new lines of
embryonic stem cells, and in April, the Senate passed its version of the bill.
By contrast,
embryonic stem cells are culled
from embryos
created and frozen in fertility labs.
The result — the second such finding in the past year — suggests that similar
cells from human testicles might have similar powers, paving the way to
creating replacement tissue for men who have suffered damage
from heart attacks or other injuries and avoiding some of the controversy surrounding
embryonic stem cells (ESC).
The new approach builds on information gleaned
from developmental studies of
embryonic stem cells (see story # 16) and one day may be used to
create healthy replacements for harmed or diseased tissue.
Renee Reijo Pera, a biologist at Stanford's Institute for
Stem Cell Biology and Regenerative Medicine, points out that earlier attempts to create offspring with sperm from embryonic stem cells resulted in short - lived mouse pups that were either giants or midg
Stem Cell Biology and Regenerative Medicine, points out that earlier attempts to
create offspring with sperm
from embryonic stem cells resulted in short - lived mouse pups that were either giants or midg
stem cells resulted in short - lived mouse pups that were either giants or midgets.
What we discovered is that we can
create literally millions or billions of these
from human
embryonic stem cells.
Scientists have
created red blood
cells from human
embryonic stem cells, in a step that they say could mean an infinite source of blood for transfusions.
One of the greatest achievements in recent biomedical research was in 2006 when Shinya Yamanaka managed to
create embryonic stem cells (pluripotent
stem cells, induced in vitro, or in vitro iPSCs) in a laboratory
from adult
cells, via a cocktail of just four genes.
Previous research in rodent disease models has shown that transplanted oligodendrocyte precursor
cells derived
from embryonic stem cells and
from human fetal brain tissue can successfully
create myelin sheaths around nerve
cells, sometimes leading to dramatic improvements in symptoms.
The debate might eventually be a moot point, as researchers continue to make convincing headway with induced pluripotent
cells, which seem to have all the properties of
embryonic stem cells but which are
created from adult
cells.
Since its inception, CIRM has sought to
create a system
from the ground up for funding research on human
embryonic stem cells to fill in the gaps left by federal funding restrictions (ScienceNOW, 12 April).
One team in Japan, and another in the US, have independently shown it is possible to produce
embryonic - like
stem cells directly
from a patient's own skin
cells without having to
create and destroy a cloned human embryo first.
The research used skin samples
from five men to
create what are known as induced pluripotent
stem cells, which closely resemble
embryonic stem cells in their ability to become nearly any tissue in the body.
Though Hwang Woo - suk, a South Korean scientist claimed to have
created the first human
embryonic clone and derived a
stem -
cell line
from it in 2004 his work was later shown to be fraudulent.
KOMP2 and IMPC researchers will begin by
creating lines of knockout mice
from embryonic stem cells produced by KOMP.
Two months ago, several scientists in Wisconsin and Japan announced that they had successfully
created a type of
stem cell from ordinary human skin
cells that seems to be able to function exactly like an
embryonic stem cell without the need to
create or destroy human embryos.
\ n3) There are «pluripotent»
stem cells which are
created from skin
cells and offer the potential for becoming different
cells similar to the hypothetical benefits of
embryonic stem cells, but they do NOT involve any moral controversy.
The Food and Drug Administration in November approved the company's plans to test
cells created from human
embryonic stem cells on 12 patients suffering
from each condition.
Embryonic stem cells can be created from cells taken from the inner cell mass (Stem Cell Basics: What are embryonic st
Embryonic stem cells can be created from cells taken from the inner cell mass (Stem Cell Basics: What are embryonic stem ce
stem cells can be
created from cells taken
from the inner
cell mass (Stem Cell Basics: What are embryonic stem ce
cell mass (
Stem Cell Basics: What are embryonic stem ce
Stem Cell Basics: What are embryonic stem ce
Cell Basics: What are
embryonic st
embryonic stem ce
stem cells?
The team that generated the insulin - producing
embryonic stem cell line, e.g., had a success rate of under six percent, using 71 eggs to produce four
stem cell lines
from the embryos they
created and destroyed.
One of those teams
created a cloned embryo
from the somatic
cells of a diabetic patient; this embryo was then destroyed in order to generate an insulin - producing
embryonic stem cell line.
2007 also saw one of the most game - changing developments in the
stem cell field; researchers learned how to
create cells like
embryonic stem cells, but instead of coming
from an embryo these
cells are
created from adult
cells, potentially
cells from any tissue in the human body.
They then extracted
embryonic stem cells from the just -
created embryos.
Stice's neural
cell kits
created from human
embryonic stem cell lines last up to six months.
In the new study, 12 patients will be treated with healthy scavenger
cells,
created in a laboratory
from human
embryonic stem cells.
But many other kinds of non-
embryonic stem cells have taken the spotlight since then, including artificial
embryonic stem cells called induced pluripotent
stem cells that can be
created directly
from patient
cells.
Last week British scientists announced that they had
created sperm
cells from embryonic stem cells for the first time.
In 2006, Wisconsin's governor dedicated $ 1 million for
creating blood products
from embryonic stem cells.