Sentences with phrase «creating cellular models»

This flexibility gives us more versatility when creating cellular models of disease and development.»

To do this, they created a cellular model of Werner syndrome by using a cutting - edge gene - editing technology to delete WRN gene in human stem cells.

In the study, members of the Gottesfeld lab, led by first author Sherman Ku, a graduate student in the Scripps Research Kellogg School of Science and Technology, created a cellular model that did reproduce this feature.

The researchers hoped to create a cellular model to parse the effects of specific gene mutations, according to a press release, but in the process they discovered that skin cells from FOP patients were much more readily converted into iPSCs than cells from healthy individuals.

Not exact matches

The next step in this line of investigation, already in development, is to learn how cellular responses vary, on a molecular level, among roots of flooded plants when the hormone is not present, which would make it possible to create a response model where this signaling path would play a key role.

In recent years, Muotri and colleagues have created in vitro cellular models of autism using reprogrammed induced pluripotent stem cells (iPSC) derived from discarded baby teeth of children with autism, work dubbed the «tooth fairy project.»

To create a more realistic mouse model of low MD activity, the team devised a new method that uses a virus to embed into the surface of MD neurons receptors that block cellular activity in the presence of a compound called clozapine - N - oxide.

Spalding, Frisén, and colleagues then created a mathematical model estimating, based on those ratios, the rate of cellular turnover within the hippocampal neurons.

Salk scientists create new molecular scissors to correct protein imbalance in cellular model of dementia

Working at the University of California, Davis, the researchers created a new cellular model for studying Down syndrome by taking skin cells from patients with Down syndrome and inducing them into a pluripotent state.

Sergiu P. Pasca, 36, assistant professor of psychiatry and behavioral sciences at Stanford, uses models of the human brain — created through cellular reprogramming technology — to explore the biological underpinnings of brain diseases like autism.

Other programs will use cellular models of heart disease created from stem cells to identify potential new drug targets.