Sentences with phrase «creating human tissue»

• Prellis Biologics, a San Francisco - based company that uses 3D printing to create human tissue and organs, raised $ 1.8 million in seed funding.

Not exact matches

Unlike the controversial method of tissue harvesting that requires some human embryos to be destroyed, the new cloning technique can use a patient's own skin cells — combined with an unfertilized human egg — to create tissue with a DNA match.

Scientists looking for new methods to make human tissue have successfully used cloning technology to create embryonic stem cells from skin cells.

PDX models are created by implanting cancerous tissue from a human primary tumor directly into immunodeficient mouse or rat models, enabling acceleration of oncology research or drug discovery and development programs.

During the first 24 hours after death, genetic changes kick in across various human tissues, creating patterns of activity that can be used to roughly predict when someone died,...

To investigate, Walker Jackson of the Whitehead Institute in Boston, Massachusetts, and his colleagues created mice with a mutation associated with the human prion disease Fatal Familial Insomnia and injected some of their brain tissue into the brains of mice without the mutation.

Oligodendrocytes, in red, create a protective sheath around nerve fibers in human brain tissue.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

The result was the largest deletion ever observed in the dystrophin gene using CRISPR / Cas9, and the study was the first to create corrected human iPS cells that could directly restore functional muscle tissue affected by Duchenne.

Minuscule blobs of human brain tissue have come a long way in the four years since scientists in Vienna discovered how to create them from stem cells.

In a first step towards creating artificial sperm cells, researchers have turned human bone marrow tissue into primitive sperm cells.

The principle component of the new panel, hydrogel — a polymer network filled with water — is safe to use in and on the human body, having already found use in applications ranging from drug delivery to creating scaffolds for tissue engineering and wound healing.

In fact, recent breakthroughs in the creation of human induced pluripotent stem cells (IPS) and the engineering of biodegradable scaffolds to create tissues may ultimately be applicable to most health conditions known to humankind.

For the first time, scientists have created vocal cord tissue starting with cells from human vocal cords.

To streamline this process, Uhlén's team has created standardized arrays containing microscopic samples from 48 kinds of normal human tissue and 20 types of tumors.

The program is tasked with creating 3 - D human tissue chips and combining them into an integrated system that mimics the complex functions of the human body, so that promising pharmaceuticals can be better tested before entering human trials.

This is a crucial advance toward creating viable human transplant tissues, says Levenberg.

The result — the second such finding in the past year — suggests that similar cells from human testicles might have similar powers, paving the way to creating replacement tissue for men who have suffered damage from heart attacks or other injuries and avoiding some of the controversy surrounding embryonic stem cells (ESC).

To demonstrate the precision of the technique and its ability to generalize to many different human tissue types, the research team created several proof - of - principle organoid arrays mimicking human tissues such as branching vasculature and mammary glands.

«First, by genetically modifying the iPS cells, we created human kidney tissue in vitro with green fluorescence.

Japanese stem cell biologist Hiromitsu Nakauchi is pioneering a technique that ultimately aims to implant human pluripotent cells into pig embryos to create replacement human tissues and organs.

Replacement tissue that avoids rejection by a patient's immune system is a step closer to the clinic, as researchers have created human embryonic stem cells carrying the DNA of specific adults.

BEIJING — Hoping to create an encyclopedia of proteins in the human body, China's Ministry of Science and Technology today kicked off a $ 40 million effort to map the human proteome — the full complement of proteins — of 10 major organs and tissues, including the heart and liver, in healthy and diseased states.

Using a two - ply of flexible, thin plastic, scientists have created novel electronic sensors that send signals to the brain tissue of mice that closely mimic the nerve messages of touch sensors in human skin.

Scientists have developed an easier, cheaper, and more efficient system for creating three - dimensional human heart tissue from stem cells.

Livia Eberlin at the University of Texas, whose team created the device, tested it on 253 human tissue samples (Science Translational Medicine, doi.org/cctx).

A new bio-ink that may support a more efficient and inexpensive fabrication of human tissues and organs has been created by researchers at UBC's Okanagan campus.

Previous research in rodent disease models has shown that transplanted oligodendrocyte precursor cells derived from embryonic stem cells and from human fetal brain tissue can successfully create myelin sheaths around nerve cells, sometimes leading to dramatic improvements in symptoms.

Some fear that people may use cloning to produce a subordinate class of humans created as tissue or organ donors.

Using both the test tube and human data, Kashuba and her team created a mathematical model that predicts the drug - to - DNA ratios in vaginal, cervical and rectal tissues and calculates the amount of drug needed to prevent HIV from infecting human tissues.

Sangeeta Bhatia, at the Massachusetts Institute of Technology, who has created tissue that can be used to bioprint human livers, knows what she is hoping for: «Someday, personalised organs on demand.»

Dr. Bruce Conklin and colleagues from Gladstone and UC Berkeley grew beating heart tissue from stem cells, creating a model of early human heart development.

So using as few of them as possible to create models of human tissue and organs saves money.

SAN FRANCISCO, CA — Scientists at the Gladstone Institutes have invented a new way to create three - dimensional human heart tissue from stem cells.

Typically, this involves creating a «scaffold» of natural or synthetic materials, seeding it with human stem cells that can differentiate themselves into particular tissue types, and providing the cells with nutrients and a physical environment that encourages them to take on the three - dimensional structures and functions of a particular body part.

Today, Griffith is a leader in a burgeoning subfield of tissue engineering that does just that: creates microversions of living human organs.

2007 also saw one of the most game - changing developments in the stem cell field; researchers learned how to create cells like embryonic stem cells, but instead of coming from an embryo these cells are created from adult cells, potentially cells from any tissue in the human body.

Professor Robert Langer, who led the research, said: «It provides a new way to create nano - based systems which we hope will provide a novel way to some day engineer tissues in the human body.»

First, while adult stem cells (stem cells isolated from a variety of adult tissues) are limited in their lifespan, hESCs can be grown and expanded indefinitely, potentially creating an infinite number of hESCs from a single human embryo.

However, while hESCs are created from human embryos, iPS cells are cells that were originally from adult tissues, such as skin from an adult body, but have been «reprogrammed» to a hESC - like state.

But a team from the Massachusetts Institute of Technology have created one that has successfully treated 15 different viruses in lab tests on human tissue and mice.

Cambridge, Mass. - September 5, 2012 - A team of experts in mechanics, materials science, and tissue engineering at Harvard have created an extremely stretchy and tough gel that may pave the way to replacing damaged cartilage in human joints.

ANN ARBOR, Mich — By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids — made from human pluripotent stem cells — researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the gut that can be caused by disorders such as inflammatory bowel disease (IBD).

Investigators from Cedars - Sinai and Emulate demonstrated how cells of a human intestinal lining created outside an individual's body mirror living tissue when placed inside Emulate's Intestine - Chips, opening the door to personalized testing of drug treatments.

«This latest work extends the capabilities of our multi-material bioprinting platform to thick human tissues, bringing us one step closer to creating architectures for tissue repair and regeneration,» says Jennifer A. Lewis, the Hansörg Wyss Professor of Biologically Inspired Engineering, the senior author on the study and a Wyss Core Faculty member.

Knowledge - based annotation aims to create a comprehensive overview of protein expression patterns in normal human tissues.

Researchers had developed the technologies needed to create organoids years before — how to grow cells in culture, how to isolate stem cells from human tissue, and how to coax the stem cells, undifferentiated and immature, to become specific types of cells at later stages of development.

Bioprinting technique creates thick 3D tissues composed of human stem cells with embedded vasculature with potential for drug testing and regenerative medicine

Gladstone scientists are engineering tissues from stem cells to create better models of human disease.

Dr. Barns, the 2016 recipient in human and mammalian genetics, uses mouse genetics to understand how ribosomes process information to create proteins for different types of cells and tissues.