Sentences with phrase «critical cell changes»
Measuring these critical cell changes is fundamental to this project and to accomplish this, the team is developing state - of - the - art imaging equipment to non-invasively measure the structural and biological changes in the nerve cells of the eye due to glaucoma.
https://www.glaucoma.org/ Not exact matches
Most importantly, these cells protected mice from developing diabetes in a model of disease, having the critical ability to produce insulin in response to changes in glucose levels.
Changes to the properties of the lipid bilayer component of the cell membrane can alter the function of proteins embedded in the membrane — proteins that regulate critical functions such as transport of materials in and out of the cell and communication with other cells.
«It is at the point of implantation that the stem cells go through this change and «mature», which is also a highly critical time for the embryo,» says Dr Lanner.
Report of the immune suppressing innervation of hepatic iNKT cells following stroke («Functional innervation of hepatic iNKT cells is immunosuppressive following stroke,» 7 October 2011, p. 101, published online 15 September 2011), and would like to highlight its relevance to previous predictions of a critical functional role for the changes in circulation cholinesterases in post-stroke patients.
«It's critical to survival that the body has ways to prevent the water concentration outside of cells from changing,» said Lowell.
He is now looking for similar changes in DNA in the cell nucleus, which contains most of the genes critical for a species» survival.
Scientists at the Gladstone Institutes discovered that changing a specific part of the huntingtin protein prevented the loss of critical brain cells and protected against behavioral symptoms in a mouse model of the disease.
The new dependency data complement the Dependency Map team's ongoing efforts to use functional genomic technologies like CRISPR and RNA interference (RNAi) to locate vulnerabilities that arise within cancer cells as they compensate for the loss of critical genes due to mutations or expression changes.
In close collaboration with oncologists at the Olivia Newton John Cancer Research Institute (ONJCRI), the technology was tested on blood samples from melanoma patients and was able to track critical changes in spreading tumor cells before, during and after treatment.
«It's similar to what we see with pre-cancerous cells which accumulate genetic changes but only become malignant when they acquire critical driver mutations that kick - off growth.»
Critical transitions across states and tipping points lay at the heart of most complex problems in modern biology, including reversible physiological adaptation to environmental change, evolution of interactions in the microbial loop, development of an adult body plan from an embryo, differentiation of a stem cell, and transition from health to disease.
The critical secondary endpoint of the change in retinal ganglion cell macular volume measured from baseline to week 48 demonstrated a statistically significant difference (p = 0.0189) between all GS010 - treated eyes and all sham - treated eyes, with untreated eyes losing 0.038 cubic mm of macular ganglion cell volume while treated eyes preserved their ganglion cell volume -LRB--0.003 cubic mm).
Changing a specific part of the huntingtin protein prevented the loss of critical brain cells and protected against behavioral symptoms in a mouse model of the disease.