Sentences with phrase «critical cell functions»

Hence, development of technologies capable of effectively overcoming these barriers for delivery of cell engineering materials, while preserving critical cell functions, is vital to success.

Soy also contains enzyme inhibitors that turn off natural enzymes needed to perform critical cell functions.

Soy also contains enzyme inhibitors that turn off natural enzyme's needed to perform critical cell functions (7, 8).

Not exact matches

The proper functioning of influenza - specific T cells is critical for efficient clearance of the virus from the lungs.

Sodium plays a role in your critical body functions by regulating the movement of water in and out of your cells.

G6PD is critical to the normal function of red blood cells.

The observation that loss - of - function mutations in DENND5A causes epileptic encephalopathy suggests that DENND5A protein controls membrane trafficking pathways critical for normal neuronal development and strengthens the argument that protein trafficking processes in cells are critical for normal neuronal development and function.

NKp46 was critical for the subsequent development of antiviral and antibacterial T cell responses, which suggests that the regulation of NK cell function by NKp46 allows for the optimal development of adaptive immune responses.

Their findings, published in the June 16, 2015 issue of Immunity, pinpoint a protein degradation pathway, which acts as an oxygen sensor in many cell types, as a critical regulator of Treg cells» function.

How microRNAs might intercept immune cells in cancer is unknown and we were able to provide insight into a critical means by which cancer cells exploit miR - 183 to dampen immune cell function.»

«This evidence suggests that the DNA timing mechanism is highly conserved, and it is possible that other time - critical functions related to the cell cycle may be regulated in a similar way.

«Our study demonstrates that ANG regulates critical functions of both clinically - relevant cell types.»

Although not nearly as well studied as neurons, astrocytes — named for their star - shaped appearance — make up one - third to one - half of all the cells in the brain and are increasingly being found to be critical for neuronal function.

Changes to the properties of the lipid bilayer component of the cell membrane can alter the function of proteins embedded in the membrane — proteins that regulate critical functions such as transport of materials in and out of the cell and communication with other cells.

Combinations of the two strike a counterbalance critical to the function of the nervous system, with inhibitory cells sculpting «noise» from excitatory cells into the arrangements behind thought and memory.

Recently, researchers have begun to describe the function of autophagy, a cellular recycling process critical for homeostasis, in germline stem - cell proliferation of C. elegans.

«Glial cells are the most abundant in the central nervous system and critical to the function of the neuronal network,» Kozai says.

While p300 apparently plays a critical role in MDS progressing to leukemia, this function is highly contextual as the protein has no obvious effect on healthy stem cells.

This led Lippman's team to propose that the ancient function of the HPAT genes is to control tip growth, which, Lippman says, is likely related to key proteins that are critical for forming cell walls.

However, researchers are still learning how best to implement immunotherapy regimens, making monitoring of the immune response during treatment development and implementation critical to predicting how the modified cells will function, and how the immune system as a whole will react.

The research provides more evidence for how these lncRNAs, which were once thought to be a type of «junk DNA» of no particular value or function, may instead play a critical role in triggering cells to become malignant and spread.

It's still early days, but researchers report that they've discovered a new small molecule that binds selectively to a long - targeted enzyme, halting its role in pain and addiction while not interfering with enzymes critical to healthy cell function.

Lipids have a variety of critical functions in all cells, including their role as the primary component of a cell's membrane.

In healthy tissues, inflammation serves a number of critical functions — fighting infections, wound healing, repair of damaged tissue and cells.

Without these tools, scientists are less able to link specific genes to cell behavior or determine how microbes interact within their environment and with one another — critical information for understanding how ocean ecosystems function.

However, hiPS cell - derived hepatocytes are only useful as an in vitro model system and for gene editing applications if they recapitulate critical hepatocyte functions.

With the help of conditional and function - selective knockout mice for the glucocorticoid receptor (GR) the lab identified critical cell types and novel mechanisms for anti-inflammatory activities of glucocorticoids in different inflammatory disease models.

This «programmed» cell death performs a critical housekeeping function that prevents damaged,...

Using genetic and epigenetic analyses coupled with powerful perturbation technologies to test gene functions in human cells and mouse models, we hope to identify the critical drivers of this disease and the basis for therapeutic responses.

Blood is an essential fluid that carries out the critical functions of transporting oxygen and nutrients to our cells.

Tissues and cells are constantly bombarded by a complex array of environmental factors that can have deleterious effects on many critical cellular functions.

IRE1 function is especially critical in B cells since the ER plays a central role in the biogenesis of antibodies in response to immunization.

In addition to a critical role in cell division, it is also clear that survivin has a function in protecting cells from apoptosis and that this pathway is followed in nearly every human tumor.

Histone deacetylases (HDACs) are critical for the differentiation and immune function of T cells (17 — 19).

In the blood, too much cholesterol can be bad, but appropriate levels of cholesterol are critical for cells to function normally.

The Akt / mTOR signaling pathway has a critical role in CD4 + T cell differentiation and function.

Recent studies have reported that GLP - 1 improves the function of renal endothelial cells (which regulate blood clotting, immune response and blood vessel activity, among other critical functions, and are impaired by insulin resistance) and can prevent some renal pathologies in diabetic rodents.

Native viral vectors can be therapeutics themselves, but they also function as a critical input to manufacturing rapidly emerging therapeutic platforms, including CAR - T and other forms of gene - modified whole - cell therapies.

Programmed death 1: a critical regulator of T - cell function and a strong target for immunotherapies for chronic viral infections.

Besides their well - known function as effector cells in allergic responses, mast cells were reported to play a critical role in innate immunity and to exert important stimulatory but also suppressive functions in adaptive immune responses.

As a monolayer of cells critical to photoreceptor function and survival, the RPE is an ideally accessible target for cellular therapy.

Protein is used in every single cell in our body and is critical for supporting neurological function, enhancing digestion and helping to balance hormones.

First, it's critical that those cell membranes have plenty of saturated fat, plenty of cholesterol, plenty of Omega - 3 and Omega - 6 because the cell membrane is how our cells communicate with the world and the cell functions.

Why you need it: plays a critical role in energy metabolism and is vital for the normal functioning of all body cells, especially nerves.

Each serving also provides high - potency B vitamins — Niacin, Vitamin B6 and Vitamin B12 — critical for every cell in your body to work at peak performance and involved in metabolism, energy production, nerve function and more.

Now, gaba is a neurotransmitter and it's critical to human function, but what gaba does is it blocks signals blocks signals between nerve cells.

Your body and its many cells depend on water for all their critical functions.

The choices you make in dietary fats are really critical, as fatty acids contribute to the formation of cellular membranes, and it's virtually impossible to have optimal biological function with impaired cell membranes.

It is critical for white blood cell (WBC) function as the WBC's encounter tremendous amounts of free radical and oxidative stress every second of the day.

Phosphatidylcholine is critical for healthy cell membrane function, keeping them fluid and flexible.