However, because the enzyme was involved in so many
critical cellular processes, the researchers knew that such an approach would yield nothing more than dead fruit flies.
However, it was unclear exactly how the mutated WRN protein disrupted
these critical cellular processes.
«We were able to use a set of cutting - edge tools to gain insight into
a critical cellular process for normal brain development, the dysregulation of which may be a manifestation of a genetic predisposition for schizophrenia,» says senior author Dr. Guo - li Ming, of Johns Hopkins University School of Medicine.
Hsieh brings expert knowledge of prostate cancer and the PI3K pathway and its effects on
a critical cellular process: translating genetic material into proteins, our cells» workhorses.
Not exact matches
The
critical moment occurs when a clinician can think across disciplines about how a
cellular process may be active in many different diseases, as Folkman did.
Understanding how
cellular processes break down these chemicals is the
critical next step.
«Obesity suppresses
cellular process critical to kidney health.»
Recently, researchers have begun to describe the function of autophagy, a
cellular recycling
process critical for homeostasis, in germline stem - cell proliferation of C. elegans.
That is when studies finally convinced scientists that the minuscule RNA snippets they had taken to calling «microRNA» were regulating
cellular and genetic
processes throughout the human body and were
critical factors in the determination of health and disease.
Previous research has described at least some of the fundamental
processes involved in healthy, on - going peripheral nerve growth regeneration, including the
critical role of mitochondria —
cellular organelles that produce adenosine triphosphate (ATP), the energy - carrying molecule found in all cells that is vital to driving nerve recovery after injury.
Since the
process of producing new brain cells on a
cellular level is similar in animals, including humans, Shors says ensuring that adolescent children learn at optimal levels is
critical.
«Our research reveals a new regulatory mechanism that coordinates two distinct intracellular
processes that are
critical to
cellular homeostasis and disease development,» said Chengyu Liang, M.D., Ph.D., a member of the USC Norris Comprehensive Cancer Center and principal investigator of the study.
«Nutrient scavenging by autophagy is a
process that tumors hijack to meet their energetic requirements and to provide the necessary
cellular building blocks for growth in a stressed tumor micro-environment» said White, «Preclinical models have demonstrated a
critical role for autophagy in multiple cancer types.»
However, whether ABL kinases have a role in the regulation of
cellular processes critical for metastasis, other than invasion, has not yet been evaluated.
Dr. Apte notes that current research suggests that NAD + biosynthesis is a
critical process in
cellular function and homeostasis in both animal models and humans.
In response to DNA damage, the checkpoint regulates and coordinates many
cellular processes critical for genomic stability, including cell cycle progression, DNA repair, DNA replication, and apoptosis.
Subsequently, he made other
critical links between the ubiquitin protein degradation system and proteins known to play central roles in vital
cellular processes.
NO is
critical signalling molecule involved in many
cellular and physiological
processes, including, but not limited to: blood circulation, immune defence and neurotransmission.
-- Magnesium is
critical in the
process that makes
cellular energy within your mitochondria.
Critical to all healing
processes, eNRG provides a boost of energy from the
cellular level.