Sentences with phrase «critical structural support»

LN stromal cells, particularly fibroblastic reticular cells (FRCs), which provide critical structural support and regulate immunity and transport properties of LNs, expand prior to the onset of metastasis and undergo significant remodelling.

Not exact matches

Actin is a filamentous protein, which together with other cytoskeletal elements forms a dynamic network of filaments that provide both structural support, as well as critical functional capabilities, to the cell.

Specifically, the team hypothesizes that microRNA miR - 24 is a key regulator of actin cytoskeleton dynamics (i.e. the inner structural support of a cell); therefore, it plays a critical role in regulating multiple disease processes, including the angiogenesis (blood vessel growth), inflammation, and fibrosis (thickening and scarring of tissue) associated with choroidal neovascularization (CNV) in wet AMD.