Sentences with phrase «crucial role your genes»
Not exact matches
In the steps of sperm - egg fusion, IZUMO1 on the spermatozoon and the IZUMO1 counter-receptor on the egg, JUNO, play crucial roles in the very first step, the formation of an intercellular bridge, and deletion of either gene leads to the failure of gamete membrane fusion.
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By knocking out individual genes in the mouse, they can systematically discover any that have a crucial biological role, or are linked with disease.
«Scientists identify proteins crucial to loss of hearing: Proteins play key role in genes that help auditory hair cells grow.»
«We identified, across the genome, that enhancer RNAs were the most common type of RNA that bound to CBP, and that by making this interaction, eRNAs play a crucial role in regulating CBP activity and gene expression.»
Now Yamanaka and his colleagues report in the journal Cell that the same combination of genes induced pluripotency in commercially available human fibroblasts (connective tissue cells that play a crucial role in healing) derived from the facial skin of a 36 - year - old woman, the joint tissue of a man, aged 69, and a newborn, respectively.
A single gene appears to play a crucial role in coordinating the immune system and metabolism, and deleting the gene in mice reduces body fat and extends lifespan, according to new research by scientists at the Jean Mayer USDA Human Nutrition Research Center (USDA HNRCA) on Aging at Tufts University and Yale University School of Medicine.
In a study led by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member Dr. Julian Martinez - Agosto, UCLA scientists have shown that two genes not previously known to be involved with the immune system play a crucial role in how progenitor stem cells are activated to fight infection.
Molecular analysis showed that heart cells in affected animals were poorly developed and had mitochondrial defects, indicating that Sap130 - Pcdha9 gene interactions play a crucial role not only in heart development but also in regulating metabolic function of the cardiac muscle.
A study carried out by the Laboratoire Neurobiologie des Interactions Cellulaires et Neurophysiopathologie (CNRS / Aix - Marseille Université), in collaboration with clinicians from Marseilles Public Hospitals (AP - HM) and scientists from the Salk Institute in San Diego (US), has revealed a new gene that plays a crucial role during early development in humans and whose under - expression may induce certain autistic traits.
«These two lines of evidence,» Tonegawa says, «corroborate that one particular gene's intactness in this particular circuit in the hippocampus plays a crucial role in being able to form distinct memories for a similar but different experience.»
The gene's apparently crucial role in embryonic development «is remarkable,» says William Kimberling, a geneticist at Creighton Medical School in Omaha, Nebraska, who studies children with BOR.
Research led by Graham Seymour, Professor of Plant Biotechnology in the School of Biosciences at The University of Nottingham, has identified a gene that encodes an enzyme which plays a crucial role in controlling softening of the tomato fruit.
MicroRNAs (miRNAs) are small non-coding RNA molecules that play a crucial role in regulating gene expression in animals and plants.
Zebrafish also express this gene, and the study showed that it plays a crucial role in embryonic development.
«We were surprised to see just how crucial this gene is for human embryo development, but we need to continue our work to confirm its role» says Dr Norah Fogarty from the Francis Crick Institute, first author of the study.
From the development of insulin and transplant surgery to modern day advances, including gene therapies and cancer treatments; animals — from mice to monkeys — continue to play a crucial role in both basic and applied research.
Together, they found that the human gene PTCHD1, which is missing in around 1 % of patients with autism, plays a crucial role in suppressing noise and allowing the brain to perceive signals unimpeded.
New research led by the University of Bristol has found that genes in the brain that play a crucial role in behavioural adaptation to stressful challenges are controlled by epigenetic mechanisms.
William Powell and Charles Maynard at the State University of New York did an ingenious bit of genetic engineering to introduce a fungus - resistant gene from wheat, creating a blight - proof American chestnut that can begin to take up its former crucial role in the eastern forest, as soon as the US government okays it as a benign genetically modified organism.
The Dockrell group is focusing on genes and cells that play a crucial role in polarisation of the immune responses and that could affect vaccine efficacy.
Small RNAs play a crucial role in genome defense against transposable elements and guide Argonaute proteins to nascent RNA transcripts to induce co-transcriptional gene silencing.
«Although we knew that the EAAT2 gene has a crucial role to play in neurological processes in human and potentially in the development of migraine, until now, no genetic link has been identified to suggest that glutamate accumulation in the brain could play a role in common migraine,» says co-senior author of the study Professor Christian Kubisch of University of Ulm, Germany (previously at the University of Cologne where he conducted his research for this study.)
Primary parental preoccupation: circuits, genes, and the crucial role of the environment.