Per started recipient cycle, the live birth rates were 50 percent with fresh vs 43 percent with
cryopreserved oocytes.
The authors write that the reasons for lower live birth rates with use of
cryopreserved oocytes remain to be established.
Per embryo transfer, the live birth rates were 56 percent with fresh vs 47 percent with
cryopreserved oocytes.
They add that the added convenience and lower cycle costs with use of
cryopreserved oocytes must be balanced against the lower live birth rates.
Researchers have been cryopreserving embryos for several decades and
cryopreserving oocytes in the past several years, but some female cancer patients lack these options.
Initiated cycles were canceled in 12 percent of fresh oocyte cycles vs 8.5 percent of
cryopreserved oocyte cycles.
Not exact matches
Of 11,148
oocyte donation cycles, 2,227 (20 percent) involved use of
cryopreserved donor
oocytes.
Compared to using fresh
oocytes (eggs) for in vitro fertilization, use of
cryopreserved (frozen) donor
oocytes in 2013 was associated with lower live birth rates, according to a study in the August 11 issue of JAMA.
Donated fresh
oocytes traditionally have been used immediately, creating embryos for transfer into the uterus, with extra embryos being
cryopreserved for later use.