Delaglio landed his first job in
a crystallography lab as a chemistry undergraduate at Syracuse University because he had some experience developing film.
I shared Mariusz's hope that he would, shortly, be able to set up the first protein
crystallography lab in his home country.
Support for the X-ray
crystallography labs came naturally, says Sliz, «but the major game change was electron microscopy.»
Not exact matches
Gordon supervises a
lab of some 20 graduate students and postdocs with expertise in disciplines ranging from ecology to
crystallography.
LiWang's
lab also collaborates with X-ray crystallographers like Carrie Partch at the University of California, Santa Cruz, because X-ray
crystallography is a powerful technique to capture static structures of proteins and their complexes at atomic and near - atomic resolution.
An international collaboration of scientists led by Omar Yaghi, a chemist with the Lawrence Berkeley National Laboratory (Berkeley
Lab), has developed a technique they dubbed «gas adsorption
crystallography» that provides a new way to study the process by which metal - organic frameworks (MOFs)-- 3D crystals with extraordinarily large internal surface areas — are able to store immense volumes of gases such a carbon dioxide, hydrogen and methane.
Using X-ray
crystallography, carried out in collaboration with the
lab of Christoph Müller, the team was able to determine for the first time the structure of Oskar's two domains, called OSK and LOTUS.
That work triggered a close race between the Cambridge University group and a rival team at MIT in deciphering tRNA's 3D structure at atomic resolution with x-ray
crystallography, with the two
labs publishing results within 2 weeks of each other.
The course is offered by Brookhaven
Labs Biology and National Synchrotron Light Source departments, and reflects an educational component of the PXRR (Macromolecular
Crystallography Research Resource), funded jointly by the National Center for Research Resources a branch of the National Institutes of Health (NIH) and the U.S. Department of Energys Office for Biological & Environmental Research.
Topic: DIALS: Advanced Data Reduction Presenter: Nicholas Sauter, Lawrence Berkeley National
Labs Presented as part of: SBGrid / NE - CAT 2014: Data Processing in
Crystallography June 5 - 6, 2014
He splits his time between the
lab, where his group studies the molecular function of key proteins in cell regulation and pathogenicity, and directing a state - of - the - art Protein
Crystallography Core Facility.
He and Sir Tom Blundell, also head of a London
lab, realized the
crystallography community needed to find a new way to work together.
CCP4 got its start in the 1970s when a number of new macromolecular
crystallography groups spawned from the pioneering
labs at the Laboratory of Molecular Biology at Cambridge and the biophysics department at Oxford.
With just a bachelor's degree, she began working in the
lab of protein
crystallography pioneer and Nobel Laureate Dorothy Hodgkin, who solved structures for penicillin, Vitamin B12 and insulin.
In college in Mississippi, he enjoyed biochemistry and did some
lab work as a synthetic organic chemist, where he was introduced to X-ray
crystallography.
He joined the laboratory of James Wang at Harvard University working on DNA toposisomerases, and subsequently the
lab of Guy Dodson at the University of York, learning protein
crystallography working on ligand discrimination in oxygen transport proteins.
Thanks to the cooperation with several technology transfer centers we are able to provide assistance in obtaining funds from the EU for the discovery of new molecules using
crystallography methods; in which our
lab service will be either a co-contractor or a subcontractor.
Since his departure from the
Lab, Chapman has continued with his interest in molecular imaging with FELs and in 2009 led an international collaboration to carry out the first experiments in this area at LCLS, where a global team introduced a new technique now called serial femtosecond
crystallography (SFX).
He has access to NMR machines at both
labs, small angle scattering at TUM, and a
crystallography facility at Helmholtz.
In the
lab of Steven Burley, she gained a solid foundation in X-ray
crystallography and solved the structures of eIF5B / IF2 and eIF2, essential GTPases involved in translation.
Williams studied solid state NMR with Ann McDermott as a chemistry graduate student at Columbia, then spent two years in the mid-1990s at the European Molecular Biology
Lab in Heidelberg learning
crystallography.
Using an integrative approach that combined electron microscopy on the Env trimer complex with PGT151 (led by the Ward
lab) with the structure of the PGT151 Fab by x-ray
crystallography (led by the Wilson
lab), the scientists were able to visualize the location of the PGT151 - series binding site on the Env trimer — which includes a spot on one gp41 protein with two associated sugars (glycans), a patch on the gp120 protein and even a piece of the adjacent gp41 within the trimer structure — «a very complex epitope,» said Claudia Blattner, a research associate in the Wilson laboratory at TSRI and member of the IAVI Neutralizing Antibody Center who, along with graduate student Jeong Hyun Lee, was a first author of the second paper.