The new research advances the ASU team's pre-existing investigations, highlighting the first time - resolved serial femstosecond
crystallography studies on Photosystem II.
In Wilson's laboratory, postdoctoral fellow Rui Xu, the study's first author, along with Staff Scientist Xueyong Zhu and Research Assistant Wenli Yu, performed X-ray
crystallography studies of the Sh2 HA protein bound to several avian - and human - type receptors.
Not exact matches
Yale University was one of the few places using x-ray
crystallography to
study the structure and function of such biological macromolecules.
Libbrecht explains that it wasn't until the development of X-ray
crystallography in the 1920s that researchers were able to
study the atomic structure of ice crystals to determine how they formed.
Hodgkin went to Somerville College Oxford to
study chemistry, then to Cambridge in 1932 for a Ph.D. in
crystallography with J. D. («Sage») Bernal, on Uncle Joseph's advice.
Think of combining
crystallography and chemical analyses to the
study of DNA, which led to the discovery of the double helix, or even of bringing the American blues tradition to young art students in the British port of Liverpool, who combined it with their native approach to harmonies and created the Beatles.
Concerns are being expressed by current SRA's that the proposed new organization of
study sections will be «too vertical» and thus have insufficient expertise in some of the basic sciences, such as protein
crystallography for example.
Even though
crystallography has been successful at determining many high - resolution structures, it is challenging to use this technique to
study structures which are not susceptible to crystallization or structural changes that do not naturally occur within a crystal.
I had completed a postdoc with Prof. Michael Rossmann during which I
studied virus - receptor relationships by using x-ray
crystallography and electron microscopy.
For this latest
study, Yaghi and Osamu Terasaki, a chemist with Stockholm University, along with collaborators from institutes in the United States, China, South Korea and Saudi Arabia, interfaced a gas adsorption apparatus with a form of X-ray
crystallography, called in - situ small angle X-ray scattering (SAXS).
An international collaboration of scientists led by Omar Yaghi, a chemist with the Lawrence Berkeley National Laboratory (Berkeley Lab), has developed a technique they dubbed «gas adsorption
crystallography» that provides a new way to
study the process by which metal - organic frameworks (MOFs)-- 3D crystals with extraordinarily large internal surface areas — are able to store immense volumes of gases such a carbon dioxide, hydrogen and methane.
The TSRI laboratories of Professor Erica Ollmann Saphire and Assistant Professor Andrew Ward are
studying the structures of these antibodies using techniques called electron microscopy, which creates high - resolution images by hitting samples with electrons, and X-ray
crystallography, which determines the atomic structure of crystalline arrays of proteins.
Normally, scientists performing X-ray
crystallography create crystals containing many copies of the protein they want to
study.
The Nature
study, led by researchers at the National Institute of Allergy and Infectious Diseases, used X-ray
crystallography to capture a three - dimensional structure of one of the conformations revealed in the Science paper.
Dr. Blanchard believes both techniques — smFRET and X-ray
crystallography — can work hand in hand to help scientists describe the functions of molecules from the perspective motion, including the other two distinct conformations identified in the smFRET
study.
Their
studies in x-ray
crystallography found subtle flaws in the honeycombs formed in the lithium and sodium iridates.
Previously such
studies could only be achieved by X-ray
crystallography, but using the electron microscope will allow us to tackle protein complexes which no one has been able to crystallise, and to do this under conditions which are much closer to those in the human body.»
To
study this, the researchers used their technique, ultrafast electron
crystallography.
Specifically, the team used neutron
crystallography to
study the location of hydrogen atoms in aspartate aminotransferase, or AAT, an enzyme vital to the metabolism of certain amino acids.
Tanner conducted his
study by using a process called protein
crystallography.
He splits his time between the lab, where his group
studies the molecular function of key proteins in cell regulation and pathogenicity, and directing a state - of - the - art Protein
Crystallography Core Facility.
This technique, which scientists are rapidly automating, may eventually displace
crystallography as the tool of choice in many cell biology
studies because it does not require the subject to crystallize and sometimes can even reveal multiple conformational states in a single experiment.
He
studies neurotransmission, vessical trafficking, and membrane fusions using X-ray
crystallography and NMR spectroscopy structure determination techniques.
The purpose of the Core for Biomolecular Structure and Function (CBSF) is to provide recombinant protein production, protein characterization, binding
studies and structural biology (X-ray
crystallography) services to MD Anderson Cancer Center and the wider Texas Medical Center.
To
study fragments the size of playing die, the researchers performed neutron
crystallography using the HIPPO (high - pressure / preferred orientation) instrument, tomographic proton radiography (invented at Los Alamos) and neutron time - of - flight radiography.
The Deaconescu Laboratory focuses on structural
studies by X-ray
crystallography, small - angle X-ray scattering and electron microscopy of protein - protein and protein - nucleic acid complexes, particularly those involved in DNA repair and transcriptional regulation.
Nobel Laureate Ada Yonath, who was awarded the 2009 Nobel Prize in Chemistry «for
studies of the structure and function of the ribosome «with X-ray
crystallography, is currently researching species - specific antibiotics.
We called them expansion segments, and initially people thought they were a remnant of evolution and didn't have any function, but current
studies by John Woolford making mutations in yeast and by other groups doing X-ray
crystallography and cryo - electron microscopy are starting to zero in on whether they may indeed be playing functional roles.
Though Gonen has published widely on the structure and regulation of membrane proteins — using electron microscopy and X-ray
crystallography — continued efforts are on pause for now in favor of developing new methods for
studying them, such as MicroED.
Williams
studied solid state NMR with Ann McDermott as a chemistry graduate student at Columbia, then spent two years in the mid-1990s at the European Molecular Biology Lab in Heidelberg learning
crystallography.
Südhof performed X-ray
crystallography and other
studies to reveal how a different group of proteins, the complexins, bind to the SNARE scaffold and help to stabilise the structure until synaptotagmin displaces them, calcium - activated synaptotagmin then sparking the fusion of the vesicle with the pre-synaptic membrane.
The Laboratory of Protein Structure (LPS) started its activities in 2008 and focuses on structural and biochemical
studies of proteins (e.g.: nucleic acid enzymes) using protein
crystallography as the primary method.
Most of our awardees are
studying asthma for the first time, bringing expertise and perspectives from a broad range of areas, including genetics, cell signaling, metabolism,
crystallography, biochemistry, pharmacology and neurobiology, among others.
Ellenberger was using
crystallography to
study DNA repair, so it was an excellent fit.