Sentences with phrase «crystallography with»

Crane continued this work after graduate school in a fellowship at California Institute of Technology, where he combined his background in crystallography with spectroscopic methods and also learned how to use photochemical techniques to initiate electron transfer reactions.
Then he combined crystallography with small angle X-ray scattering to visualize the entire enzyme and observe how ATP powers its strand passage reaction.
To do this work, Crane is integrating X-ray crystallography with electron microscopy and pulsed dipolar electron spin resonance spectroscopy.
In this work, she combines crystallography with techniques from biochemistry and spectroscopy to understand these enzymes.
Henry Chapman, who worked at Lawrence Livermore National Laboratory (LLNL) from 1996 to 2007, will be presented on Jan. 26 with an honorary doctorate by Sweden's Uppsala University for his work on developing techniques for imaging and crystallography with intense X-ray pulses.
Henry Chapman, who worked at Lawrence Livermore National Laboratory from 1996 to 2007, will be presented with an honorary doctorate by Uppsala University for his work on developing techniques for imaging and crystallography with intense X-ray pulses.
Hodgkin went to Somerville College Oxford to study chemistry, then to Cambridge in 1932 for a Ph.D. in crystallography with J. D. («Sage») Bernal, on Uncle Joseph's advice.
Ultrafast electron crystallography with the use of a tilted optical geometry technique afforded the necessary atomic - scale spatial and temporal resolutions.

Not exact matches

The technique, called crystallography, was a bit like making a shadow animal on the wall with one's hand and a flashlight.
After graduating in 1990, Ban went to the United States to do his Ph.D. at UC Riverside with crystallography expert Alexander McPherson.
We report direct determination of the structures and dynamics of interfacial water on a hydrophilic surface with atomic - scale resolution using ultrafast electron crystallography.
In particular, ELETTRA, a third generation synchrotron radiation facility dedicated to many aspects of materials science such as crystallography, spectroscopy, and lithography, has put me in touch with a very broad scientific community and allowed me to find opportunities.
For those of you who aren't familiar with x-ray crystallography, I'll describe this horror show of a research field, which produces fascinating and useful data via tedium and — yes — blind luck.
The new 3 - D structure, which was obtained using X-ray crystallography and electron microscopy, revealed that the outer surface of the Zika NS1 protein has substantially different electrical - charge properties than those of other flaviviruses — indicating it may interact differently with the members of an infected person's immune system.
There was more room for them in new, expanding sciences such as x-ray crystallography, particularly with the tiresome work required before the advent of the electronic computer and automatic methods.
These three institutes have long collaborated; in 2002, they teamed up with the nearby Institute for Structural Biology (IBS), which contributed its complementary expertise in crystallography, nuclear magnetic resonance, and electron and mass spectrometry to form the Partnership for Structural Biology (PSB).
The prize will be equally split between biophysicist Venkatraman Ramakrishnan of the MRC Laboratory of Molecular Biology in Cambridge in England, biochemist Thomas Steitz of Yale University and molecular biologist Ada Yonath of the Weizmann Institute of Science in Rehovot, Israel, for their work in using x-ray crystallography to get a precise, atomic - scale map of the ribosome — the protein - making machine in all cells with nuclei that makes life possible.
Think of combining crystallography and chemical analyses to the study of DNA, which led to the discovery of the double helix, or even of bringing the American blues tradition to young art students in the British port of Liverpool, who combined it with their native approach to harmonies and created the Beatles.
This marks the second time in four years that the chemistry Nobel has been awarded to someone working with x-ray crystallography; in 2006 Roger Kornberg took the prize for detailing the structure of messenger RNA, which is the molecule that carries the information the ribosome uses to build proteins, such as insulin or hemoglobin.
Yonath is just the fourth woman ever to win the Nobel Prize for Chemistry and the first since 1964 when Dorothy Hodgkin won for her x-ray crystallography work with penicillin and cholesterol.
The key to that is x-ray crystallography in which x-rays are shone through a crystal filled with ribosomes, creating a scatter pattern that reveals their inner workings (detected by CCDs, the inventors of which were honored yesterday with the 2009 Nobel in Physics).
We used mutations with natural and unnatural amino acids, electrophysiological recordings, and x-ray crystallography to identify a charge transfer center in voltage sensors that facilitates this movement.
Gordon supervises a lab of some 20 graduate students and postdocs with expertise in disciplines ranging from ecology to crystallography.
X-ray crystallography, a technique that can produce images of molecules with exquisite detail, has one drawback: It works best on crystals, in which many copies of a molecule are lined up in a regular array.
Arrangements with the then head of the school of crystallography, Julia Goodfellow, were swiftly sorted out, and since October 2001 I reside at Birkbeck for 2 days per week (working from home the rest of the time).
«One of the most important results of this work is that the structure obtained at LCLS is almost identical to the structure obtained with traditional crystallography, despite the fact that the LCLS data were collected from crystals 100 times smaller by volume and at room temperature,» Cherezov stressed.
Complexes with HAs from the group 1 H1 and the group 2 H3 subtypes analyzed by x-ray crystallography showed that the antibody bound to a conserved epitope in the F subdomain.
Celebrating crystallography's centennial; how climate pushes malaria uphill; roundup of daily news with David Grimm.
Yes, we've all heard of Marie Curie's exploits with radioactivity (1890) and Rosalind Franklin's indispensable x-ray crystallography work toward the discovery of the DNA double - helix (1953), but how many of us know that Nettie Maria Stevens (1905) demonstrated that the X and Y chromosomes were responsible for determining the sex of an individual?
«We synthesized a new compound, demonstrated its effectiveness with biological data, and learned more about its interactions with proteins through X-ray crystallography and computational analysis,» says UConn associate professor of chemistry José Gascón, a specialist in quantum and molecular mechanics.
I had completed a postdoc with Prof. Michael Rossmann during which I studied virus - receptor relationships by using x-ray crystallography and electron microscopy.
For this latest study, Yaghi and Osamu Terasaki, a chemist with Stockholm University, along with collaborators from institutes in the United States, China, South Korea and Saudi Arabia, interfaced a gas adsorption apparatus with a form of X-ray crystallography, called in - situ small angle X-ray scattering (SAXS).
Thatcher could support the reforms, Agar argues, because she «had lived the life of the working research scientist, as a final - year chemistry student in Dorothy Hodgkin's x-ray crystallography laboratory, as an investigator of glues for BX [plastics company] and as a food chemist for Lyons & Co.... [I] t was precisely because Thatcher knew what scientific research was like that made her impervious to claims that science was a special case, with special features and incapable of being understood by outsiders, and therefore that science policy should be left in the hands of scientists.
LiWang's lab also collaborates with X-ray crystallographers like Carrie Partch at the University of California, Santa Cruz, because X-ray crystallography is a powerful technique to capture static structures of proteins and their complexes at atomic and near - atomic resolution.
To develop better drugs, scientists want to use a process called x-ray crystallography to develop a complete picture of how integrase inhibitors — the class of HIV drugs that target integrase — interact with the virus.
An international collaboration of scientists led by Omar Yaghi, a chemist with the Lawrence Berkeley National Laboratory (Berkeley Lab), has developed a technique they dubbed «gas adsorption crystallography» that provides a new way to study the process by which metal - organic frameworks (MOFs)-- 3D crystals with extraordinarily large internal surface areas — are able to store immense volumes of gases such a carbon dioxide, hydrogen and methane.
In collaboration with Dr Raphael Gasper - Schönenbrücher from the work group Protein Crystallography, headed by Prof Dr Eckhard Hofmann, they solved the atomic structure of GtCPES.
The TSRI laboratories of Professor Erica Ollmann Saphire and Assistant Professor Andrew Ward are studying the structures of these antibodies using techniques called electron microscopy, which creates high - resolution images by hitting samples with electrons, and X-ray crystallography, which determines the atomic structure of crystalline arrays of proteins.
Using X-ray crystallography, carried out in collaboration with the lab of Christoph Müller, the team was able to determine for the first time the structure of Oskar's two domains, called OSK and LOTUS.
The tiny cocoons were by far the smallest protein crystals ever imaged with X-ray crystallography, and the results point the way to using even smaller crystals — or even uncrystallized proteins and other biomolecules — for structure analysis.
A team of researchers led by the Department of Energy's Oak Ridge National Laboratory used neutron macromolecular crystallography to investigate the different states of three glaucoma drugs as they interact with the targeted enzyme, human carbonic anhydrase II (hCA II).
Time - lapse crystallography was used by National Institute of Environmental Health Sciences (NIEHS) researchers to determine that DNA polymerase, the enzyme responsible for assembling the nucleotides or building blocks of DNA, incorporates nucleotides with a specific kind of damage into the DNA strand.
That work triggered a close race between the Cambridge University group and a rival team at MIT in deciphering tRNA's 3D structure at atomic resolution with x-ray crystallography, with the two labs publishing results within 2 weeks of each other.
Electron cryo - microscopy is emerging as a complementary approach in cancer drug design to X-ray crystallography — which involves generating highly ordered crystals of proteins and hitting them with X-ray radiation.
In Wilson's laboratory, postdoctoral fellow Rui Xu, the study's first author, along with Staff Scientist Xueyong Zhu and Research Assistant Wenli Yu, performed X-ray crystallography studies of the Sh2 HA protein bound to several avian - and human - type receptors.
But BRCA2 is a large, fussy molecule, difficult to isolate and characterize with x-ray crystallography.
To find the structure, the MIT team used X-ray crystallography, which they performed in a special chamber with no oxygen.
Access to instruments for neutron crystallography on the high flux neutron source of the ILL In collaboration with the ILL, access is provided to two instruments for neutron crystallography.
Conventional techniques used to image proteins, such as X-ray crystallography and nuclear magnetic resonance imaging, don't work with fibrous structures such as amyloids.
With cutting - edge crystallography and microscopy techniques, Christopher Barnes aims to reveal — in extreme detail — how newly isolated antibodies neutralize HIV - 1 by latching onto viral envelope proteins.
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