Sentences with word «csc»

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nbA (New Business Accelerator) a web based application is being developed by CSC with an objective to improve the efficiency of the policy is...

As shown in Fig. 5A, ectopic expression of KLF4 indeed significantly increased CSCs population in 231BrM cells.

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Niclosamide inhibited proliferation of breast CSC - like cells [44].

Therefore, it is plausible that there are distinct populations of metastatic CSCs that can proliferate in the niche of specific distant organs.

In vivo model of hypoxic CSC effect.

Students frequently mention how much the teachers at CSCS care about them (and how much they sacrifice to work there).

Together, results from established assays for CSC activity show that the cycling hypoxia - selected subpopulation has an increased ability of tumor initiation and tumor - sphere formation.

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B, CSCs isolated from 231BrM infected with lentivirus of miR7 or KLF4 expression plasmids were seeded on top of mouse brain endothelial cells or Matrigel.

We also examined the invasive ability of these cells using Matrigel invasion chamber and found that miR - 7 was also able to block the invasion of CSCs through Matrigel (Fig. 4A, right).

Our results led us to speculate that there might be a metastatic subpopulation within stem - like cancer cells since other studies have shown that CSC phenotype alone may exhibit invasive property in vitro but is inadequate to determine or predict in vivo metastasis.

However, as demonstrated by a recent report from Stuelten and colleagues [13], the complexity of CSC markers continues to pose challenges for identifying and isolating the putative tumor stem cell populations by the cell - sorting approach.

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Tony Mauro of Legal Times reports that the Supreme Court justices have invited the view of the solicitor general on a petition for cert filed in Cable News Network Inc. v. CSC Holdings, which concerns the issue of whether, under the Copyright Act of 1976, Cablevision's on - demand service infringes the petitioners» exclusive copyrights by copying, storing and transmitting its programs without an additional license.

Share your photos on Twitter or Instagram with #CSCspotted - once a month, we pick our favourite entrant to win a brand new CSC bag!

CSC hypothesis has resulted in incredible impact on the understanding and insight into tumor biology.

CSC Sport is a high - quality and longstanding expert in the synthetic grass industry and a key player in the Dutch market.

Supervisor — Pharmacy Operations Manager, CSC Pharmacist.

Therefore, we hypothesize that hypoxia / reoxygenation cycles may provide the driving force to select for a highly metastatic breast CSC subpopulation.

Our findings suggest that this is also true in breast cancer as EGFR inhibition blocked the hypoxic CSC effect in ER - α — positive tumors.

Chaffer and Marjanovic, a former research assistant in the Weinberg lab, studied non-CSCs from luminal - and basal - type cancers and determined that cells from basal cancers are able to switch relatively easily into CSC state, unlike luminal breast cancer cells, which tend to remain in the non-CSC state.

When these cells are exposed to certain signals, including those from TGFß, the repressive marks are removed and ZEB1 is expressed, thereby converting the basal non-CSCs into CSCs.

Note: Students with classes at Middleton High School will be expected to attend classes on CSCS Program Development Days.

Nevertheless, we believe hypoxia is only a partial driving force for the metastatic CSC enrichment.

Year after year, CSCS students amaze and delight their audiences of peers, educators and Middleton community members with their stories of exploration, growth, and reflection.

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CSC provides Curriculum Consultation, Teacher Development and Resource Development worldwide.

University of Victoria Peter B. Gustavson School of Business PO Box 1700 STN CSC Victoria BC V8W 2Y2 Canada Phone: [phone] Fax: [phone] [email protected] More contact information

We investigated its putative effects on small cell lung cancer (SCLC) circulating tumor cell (CTC) cell lines which are operative in metastasis and exhibit a phenotype overlapping with CSCs [Hamilton, manuscript submitted].