Sentences with phrase «culprit in a disease»

While axonal degeneration appears to be a major culprit in diseases like multiple sclerosis, it also paradoxically plays an important role in properly wiring the nervous systems of developing embryos.

Even before they determine the genetic culprit in a disease, however, scientists can use its SNP pattern to identify those who have the genetic signature of risk for that disease.

Scientists have identified the likely culprit in a disease that has devastated sea stars along the west coast of North America.

Bapineuzumab is an antibody that targets β amyloid, a protein fragment that accumulates in the brains of Alzheimer's patients and is widely thought to be a key culprit in the disease process.

And yet a lot of people misguidedly believe sugar is the culprit in this disease.

Not exact matches

With fat considered the culprit in heart disease, it's no surprise the Dietary Guidelines for Americans in the 1980s suggested reducing total fat, saturated fat, and dietary cholesterol intake to prevent coronary heart disease.

What we've since come to find out, is fat wasn't the culprit behind the boom in obesity, diabetes, and heart disease.

It's no longer a secret that the margarine Americans have been spreading on their toast, and the hydrogenated fats they eat in commercial baked goods like cookies and crackers, is the chief culprit in our current plague of cancer and heart disease.22 But mainline nutrition writers continue to denigrate butter — recommending new fangled tub spreads instead.23 These may not contain hydrogenated fats but they are composed of highly processed rancid vegetable oils, soy protein isolate and a host of additives.

The sugar industry paid scientists in the 1960s to play down the link between sugar and heart disease and promote saturated fat as the culprit instead, newly released historical documents show.

An 1884 newspaper illustration, for example, depicted a skeleton disguised as a fruit seller offering produce to little children, suggesting that raw, unboiled fruits and vegetables led to cholera.17 The actual culprit, especially in such turn - of - the - century urban metropolises as New York City, with its inadequate, overloaded water and sewer systems, was most likely bacteria residing on the outside of the produce, or contaminated water or milk that happened to be ingested, rather than anything in the produce itself.18 Given the laxative effect of fruits and vegetables if consumed in excess, however, it is understandable that people assumed fresh produce might contribute to diseases with symptoms that included diarrhea.

(Gum disease, or gingivitis, is a culprit in adults, but not usually in children.)

«Dysfunctional gene may be culprit in some Crohn's disease cases.»

Usually, state health departments rely on standard questionnaires to find a common culprit for a cluster of reported illnesses, says Samuel Crowe, an epidemiologist at the Centers for Disease Control and Prevention in Atlanta, who led the study.

Researchers could now see the culprits and distinguish between similar diseases such as anthrax, cholera and, yes, bubonic plague, which was isolated in 1894 and named Yersinia pestis in honor of Swiss microbiologist Alexandre Yersin.

This protein is part of the enzymatic engine that churns out amyloid beta — a key molecular culprit in Alzheimer's disease — by snipping it out of a larger precursor protein called APP.

But when blood tests and clinical evaluation were done with the help of the regional Texas Border Infectious Disease Surveillance project, a surprising culprit was unmasked: dengue hemorrhagic fever, a deadly viral disease usually regarded as a risk only in the tDisease Surveillance project, a surprising culprit was unmasked: dengue hemorrhagic fever, a deadly viral disease usually regarded as a risk only in the tdisease usually regarded as a risk only in the tropics.

But Cunningham, who recently spent several weeks in India investigating the vulture die - off, says that an infectious disease may be the culprit.

The culprit: fumes from nitrogen - rich fertilizers and animal waste combine in the air with combustion emissions to form solid particles, which constitute a major source of disease and death, according to the new study.

But the culprit spreading the disease is probably the Asian citrus psyllid, an aphid - size insect first sighted in Florida in 1998.

«Our interest in the body's own (innate) immune system as the culprit began when we discovered that immune system agents become activated in a laboratory model of Huntington's Disease,» he says.

In advancing care for JIA, researchers are keen to identify the culprit cells or genetic signatures behind the disease in order to tackle iIn advancing care for JIA, researchers are keen to identify the culprit cells or genetic signatures behind the disease in order to tackle iin order to tackle it.

The incidence of these diseases has become more prevalent in recent decades, and scientists have identified a possible culprit: salt.

Davies, now at the Litwin - Zucker Center for the Study of Alzheimer's Disease and Memory Disorders in Manhasset, New York, suspects a different culprit.

Although more than 250 different Aspergillus species are found in nature, and most contribute spores to the air we breathe, over 80 % of human disease is caused by one particular culprit called Aspergillus fumigatus.

The gene, called NF1, was pinpointed in 1990 as the culprit in neurofibromatosis (NF), a disfiguring and potentially deadly disease that affects one in 3500 people.

Named for a town in upstate New York, coxsackievirus is one of the culprits behind hand, foot and mouth disease, a common childhood illness.

The propensity of proteins to stick together in large clumps — termed «protein aggregation» — is the culprit behind a variety of conditions including Huntington's, Alzheimer's, and mad cow diseases.

«Culprit implicated in neurodegenerative diseases also critical for normal cells.»

Biggest mysteries Kidney disease: Farm workers in Central America, India and Sri Lanka are dying in staggering numbers from a rare kidney disease, with pesticides fingered as a potential culprit.

In the brain, these sticky barnacle - like proteins are believed to be the culprits behind the memory - robbing ravages of Alzheimer's disease.

Clearing land for farms and developments has long been assailed for destroying amphibian habitats, but the main culprit in their deaths, according to the report, is chytridiomycosis, an infectious disease caused by a waterborne fungus.

Shortly after the first encephalitis cases emerged, a team from the Centers for Disease Control and Prevention (CDC) lab in Fort Collins concluded from antibody tests that the culprit was St. Louis encephalitis, a disease that is endemic in the southern United Disease Control and Prevention (CDC) lab in Fort Collins concluded from antibody tests that the culprit was St. Louis encephalitis, a disease that is endemic in the southern United disease that is endemic in the southern United States.

But because the virus can not be grown in culture, scientists can not satisfy the classic tests for identifying the culprit of a disease: four criteria collectively referred to as Koch's postulates.

One of their findings was a variant in a gene called Ret that had not been previously associated with the disease, although other variations in Ret had been fingered as culprits.

If that sounds potentially dangerous, it is: Such genes are often the culprits behind tumor - causing mutations and have been implicated in several neurological diseases.

The culprit in Guinea worm disease is a roundworm parasite called Dracunculus medinensis, whose larvae dwell in microscopic water fleas.

Amyloid beta oligomers now are widely believed to be the culprit in the onset of Alzheimer's disease and subsequent memory loss.

That points to an environmental culprit that may work in concert with genetic factors to drive this aggressive, fatal disease.

The findings bolster the predominant hypothesis that amyloid accumulation is the primary culprit in Alzheimer's disease, says Alison Goate, a geneticist who studies Alzheimer's disease at Washington University in St. Louis.

A more complete catalog could help researchers track down the culprit genes in patients with rare, unexplained diseases.

Using archival documents, a new report published online by JAMA Internal Medicine examines the sugar industry's role in coronary heart disease research and suggests the industry sponsored research to influence the scientific debate to cast doubt on the hazards of sugar and to promote dietary fat as the culprit in heart disease.

«Our research on BBB disruption and the role certain proteins play in neuro - inflammation has advanced our efforts to explore unexpected culprits in neurological diseases,» Akassoglou said.

The researchers, who previously identified NOTCH1 as a genetic culprit in human CAVD, created mice that had shorter telomeres and were also missing one copy of the NOTCH1 gene, since mutation of NOTCH1 alone failed to induce valve disease in mice.

Evidence points to beta amyloid (Aβ) peptide accumulation as a culprit in preclinical Alzheimer's disease.

Scientists at Salk Institute and The Scripps Research Institute identify mutant protein as culprit in Charcot - Marie - Tooth (CMT) diseases

On that list is Vitamin E, a powerful antioxidant found in oils, nuts, seeds, whole grains and leafy green vegetables, which is associated with slower cognitive decline, a lower risk of dementia, and reduced accumulation of beta - amyloid proteins — a key culprit in Alzheimer's disease.

Sugar — that sweet stuff that's present in nearly three - quarters of the products we see on grocery market shelves — is not as sweet as it looks and may be the primary culprit behind the rise of metabolic diseases and non-fatty liver disease.

In short, evidence doesn't seem to support focusing largely on cholesterol as the culprit in heart disease, and there are a variety of other factors that may be much more importanIn short, evidence doesn't seem to support focusing largely on cholesterol as the culprit in heart disease, and there are a variety of other factors that may be much more importanin heart disease, and there are a variety of other factors that may be much more important.

It found essentially no association between saturated fat — long considered a major culprit in raising LDL or «bad» cholesterol levels — and heart disease.

Some of the most common culprits I see in my practice are herpes simplex (HSV), Epstein - Barr (EBV), and Lyme disease.