Another option is to take a skin sample,
culture cells called fibroblasts and freeze them.
Not exact matches
Producing «clean» meat by
culturing cells — instead of raising or slaughtering animals - is a new frontier in food production, but will it require a new regulatory framework, and what should we
call it?
In giant vats, muscle and fat
cells will be
cultured then made into so -
called «clean meat», without, if the technology progresses, a single animal having to die.
Shukla and colleagues discovered that a small drug molecule
called BX795, which is sold to labs for use in experiments, helped clear HSV - 1 infection in
cultured human corneal
cells, in donated human corneas, and in the corneas of mice infected with HSV - 1.
Working in
cell cultures and mice, researchers at Johns Hopkins have found that an experimental drug
called fostamatinib combined with the chemotherapy drug paclitaxel may overcome ovarian cancer
cells» resistance to paclitaxel.
Researchers then tested
cell cultures and mouse models by using a gene editing process
called CRISPR - Cas9 to demonstrate how the presence or absence of myomaker and myomerger — both individually and in unison — affect
cell fusion and muscle formation.
The researchers — James Robl, a developmental biologist and his colleagues at the University of Massachusetts at Amherst, and Steve Stice at Advanced
Cell Technology in Worcester, Massachusetts — inserted a marker gene fused with a gene for resistance to the chemical neomycin into a
culture of connective tissue
cells called fibroblasts.
By studying the same process in
cultured cells, the scientists found that the light stimulated a molecular chain reaction that activated a normally dormant protein
called TGF - beta 1.
They added the modified adrenaline compound,
called CP - 331679, to
cultured human fat
cells, and saw that the receptors were activated and were triggering a biochemical cascade inside the
cell.
They hit upon a small organic compound
called SB 247464 that stimulated the growth of mouse white blood
cells in
culture and in living mice.
The enzyme,
called tankyrase, may prove useful for extending the lives of
cultured cells grown to repair burned skin and other damaged tissue.
The study team removed fibroblasts (skin
cells) from DBA patients, and in
cell cultures, using proteins
called transcription factors, reprogrammed the
cells into iPSCs.
Writing in the May 4 online issue of the journal Scientific Reports, researchers at University of California, San Diego School of Medicine used a powerful statistical tool
called «design of experiments» or DOE to determine the optimal
cell culture formula to grow and produce hPSCs.
In the lab, the herbicide 2,4 - dichlorophenoxyacetic acid (sold as weed killer and
called 2,4 - D) can prompt
cells in
culture to elongate, build a new
cell wall, and start dividing to form embryos.
Three types of colon cancer
cells grew faster, producing about 50 to 60 percent more
cells within 24 hours, with the bacteria than they did when
cultured with no bacteria or with a harmless, milk - fermenting bacterium
called Lactococcus lactis.
In this study, Nicchitta and his colleagues treated tissue
culture cells with a stress - inducing agent
called thapsigargin.
Her team decided to try a
cell - growing approach,
called 3D
cultures, that's been successful for other types of
cells that need to form complex structures as they grow.
Drugs that activate this novel stress response pathway, which they
call the mitochondrial - to - cytosolic stress response, protected both nematodes and
cultured human
cells with Huntington's disease from protein - folding damage.
To replicate these
cell culture results, Rani used human stem
cells to grow neurons into what is
called a mini brain.
In the current issue of Nature Medicine, John Pezzuto of the University of Illinois at Chicago and his colleagues report that a compound
called betulinic acid triggers apoptosis or programmed
cell death, in
cultured melanoma
cells.
The researchers, working with
cell cultures, first observed how individual tumour
cells kill specific
cells in the vascular wall,
called endothelial
cells.
Next, Grima looked at
cell death in
cultured neurons with a healthy or a mutant form of Huntingtin, or with a mutant form of Huntingtin that was treated with small amounts of an experimental drug
called KPT - 350, one that prevents a nuclear export protein, Exportin - 1, from shuttling proteins and RNA out of the nucleus.
Cells from her malignancy were
cultured and used to start a
cell line,
called HeLa, which lives on to this day in research labs around the world.
Using her new
culture system, she joined forces with colleagues to research which
cells in an embryo contribute to which parts of the adult animal, a process
called fate - mapping.
To investigate, a team led by Gerburg Wulf, MD, PhD, a physician scientist in the Hematology / Oncology Division at Beth Israel Deaconess Medical Center (BIDMC) and an Associate Professor of Medicine at Harvard Medical School,
cultured breast
cells called primary mammary epithelial
cells (MECs) in the presence of EBV.
Previous attempts to maintain
cultures of the so -
called nephron progenitor
cells often failed, as the
cells died or gradually lost their developmental potential rather than staying in a more medically useful precursor state.
The team conducted additional experiments in which mouse breast tumors were sampled to generate so -
called organoids — spheres of
cells that grow in three - dimensional
culture.
They diluted the microbial sample such that they could add a single
cell per
culture well filled with their new media via a technique
called dilution - to - extinction.
The research builds on the team's previous work with a technique
called three - dimensional
culture, which involves incubating stem
cells in a floating ball - shaped aggregate, unlike traditional
cell culture in which
cells grow in a flat layer on the surface of a
culture dish.
The researchers removed the organ of Corti, which is housed within a seashell - shaped cavity
called the cochlea and contains sensory hair
cells, from newborn mice and kept the
cells alive in
culture plates.
In
culture dishes, ramping up the expression of just four genes can turn skin and other
cells into so -
called induced pluripotent stem (iPS)
cells.
Further, when TILs have been used for such purposes, the proportion of what Harari
calls the «juiciest» T
cells — those recognizing mutations on cancer
cells — tends to decline significantly when the
cells are expanded in
culture.
In their recent study, the UCSF team reports the discovery that a class of commonly prescribed Type - 2 diabetes drugs,
called TZDs (thiazolidinediones, such as Actos and Avandia), promoted the conversion of white fat
cells into brown (in mice and
culture dishes) by stabilizing the PRDM16 protein.
This protocol video demonstrates how to surface - coat
cell culture plates and transwell inserts with Cultrex ® Basement Membrane Extract, also
called Cultrex ® BME.
According to Dr. Burgess, the team is now working to extend the period that sperm
cells can be
cultured, so there is more time to select
cells that have the foreign gene inserted in specific areas of the genome in what is commonly
called a «targeted gene knockout.»
Working with prostate
cell cultures, Meier and two students, Ze Liu and Mandi Hopkins, found the fatty acids bind to a receptor
called FFA4, for «free fatty acid receptor 4.»
While learning how to
culture rhinovirus C, Palmenberg's research team discovered the virus only infects certain lung
cells that express a particular genetic form of a
cell - surface molecule
called cadherin - related protein 3 (CDHR3).
Once isolated these
cells can be grown in a liquid medium of nutrients,
called culture.
After a two - day
culture period, liver
cells formed tightly packed cellular aggregates,
called spheroids, and took on a liver - like appearance.
The most well - known of these are so -
called «senescent»
cells, originally characterized by Leonard Hayflick as mitotic
cells that reached growth arrest after a limited replicative lifespan (later associated with telomere attrition) under unphysiological conditions in
culture.
Recently, Drs. Nociari and Boulan have identified a family of cyclic sugars,
called beta - cyclodextrins (beta - CDs), that bind and reduce bisretinoid - lipofuscin levels from
cultured cells.
By activating a gene
called Ras in
cells bathed in a very specific
culture medium, scientists were able to cause embryonic stem
cells — which originate from the inner
cell mass of the blastocyst — to become more like the trophoblastic stem
cells that give rise to the placenta from the outer portion of the blastocyst.
The
cells are
called lung spheroid
cells for the distinctive sphere - like structures they form in
culture.
(A) Different biomolecules on the surface of prepared silver nanoparticles (linker not shown); (B) in
cell culture media the nanoparticle - water interface is composed of ligands and ions but also of proteins, the so -
called protein corona.
Using a mouse model for this disease, which in humans involves the destruction of white matter in the brain, a research team led by Albee Messing, director of the UW — Madison Waisman Center, found that a protein behind the symptoms of the disease,
called GFAP, is broken down more rapidly in the body than researchers previously found in
cell culture studies.
A flavorful component of cinnamon oil,
called cinnamaldehyde, may help prevent colon cancer, according to a tissue
culture study of human colon cancer
cells published in the May 2010 issue of the journal «Molecules.»
Three capsules per day provide a 15 billion live
cell count ** of 13 species of beneficial
cultures including soil - based probiotics
called Homeostatic Soil Organisms (HSOs).
The educational force of the wider
culture is now the primary site where education takes place, what I have
called public pedagogy — modes of education largely produced, mediated, and circulated through a range of educational spheres extending from the new media and old broadcast media to films, newspapers, television programs, cable TV,
cell phones, the Internet, and other commercial sites.
While banning
cell phones and
calling in the cops might be options of last resort, they won't do much to improve a school's
culture.
«Among other things, the NAS Report
calls for the Environmental Protection Agency to implement a toxicity testing strategy that is based on non-mammalian systems and human
cells in
culture [in vitro],» Rene explains.