Sentences with phrase «culture models with»

However, this coupling does not exist in cell culture models with exogenously expressed c - MYC — the type of systems that are mainly used to investigate glutamine addiction in cancer.

Not exact matches

With one recently - auctioned 14 - bedroom, two - pool mansion on Park Lane Circle being modelled on the Palace of Versailles, it's clear that the residents of Bridle Path have a cultured eye for the world's best things.

Similarly, having led my own companies through fairly major changes - combined with thorough research — I have developed a model for culture driven transformation (CDT).

However, we had not done enough due diligence to understand how the entirety of the company would integrate with our business model, team, and culture.

This often takes some sort of live meeting in which leaders can talk with other leaders about the direction and strategy of the organization and revise their mental models of how they'll need to show up every day and model the culture of the future.

In a time when many companies struggle with employee retention, his family business model has supported a culture where many employees have stayed for more than 20 years and refer their family members for employment.

This reduction in force is consistent with an overall turn - around program that began a year ago to correct regulatory compliance issues, reset our culture and values, increase operational efficiency, and introduce a new SaaS product and business model.

To build a team that is reflective of the time, you have to maybe look outside traditional models... Oftentimes we're looking for, obviously people with experience, but also people that are creative and passionate about culture.

Small business owners see that this reality TV culture has been established — but they don't associate with those people as role models or as the types of people they consider themselves to be.

«Based on the innovative model from Start - Up Chile, Start - Up Chile launched with a mandate to attract foreign entrepreneurs to the local consumer market and foment domestic entrepreneurial culture»

Kelly suggests leaders must «model the culture: spending time with employees, treating people with respect, having fun, being there for them personally and professionally, and putting people first — with empathy, kindness and compassion.»

The Swedish model has to do with culture as well as economics.

The Church, and the papacy in particular, has broken with the «Constantinian» model of power in order to become, in accord with the vision of the Second Vatican Council, the «teacher and evangelist of culture,» a role that retrieves and renews the New Testament task of Peter to «strengthen the brethren.»

Whenever pluralism becomes too content with a relaxed model of «dialogue,» it can ignore the need for conflict and the actualities of systematic distortions in the personal (psychosis), historical (alienation and oppression) and religious (sin) dimensions of every person, culture and tradition.

The Christ - without - culture model induces contentment with being a subculture.

The confidence has many roots: the steady decline of models of theology in which «critical appraisal» is the dominant task; receptiveness toward and fresh engagement with classical thinkers, patristic, medieval and Reformation; a sense that the Enlightenment is only one episode in the history of one (Western) culture and not a turning point in the history of humankind; the work of a number of gifted and independent - minded theologians now at the height of their powers who have shown the potency of constructive doctrinal work.

This article is arguably hypocritical as well as stomach - churning, since it begins with the suggestion that «Because of the amazingly diverse multicultural contexts in which pastoral ministers are called upon to work today, it is impossible to prescribe one liturgical model that will be always and everywhere appropriate»: this flexible and open - minded liturgist then proceeded to argue in The Tablet that only the Mass of Paul VI is always and everywhere appropriate and that its very existence automatically abrogated all previous liturgies for ever: presumably those who prefer the older form are not to be given the dignity of a group or «culture» to be catered for by his free and easy multicultural ways, but are to be simply dismissed as a bunch of liturgical perverts.

There can, they profoundly believe, be no survival without collaboration: and the idea that if we are to thrive in a predominantly secular culture we should informally come to a kind of concordat with it, rather on the model of the Anglican Establishment, has become very powerful in the English Catholic Church.

This tentative model for understanding the causes of problem drinking is offered in the report of the Cooperative Commission on the Study of Alcoholism: «An individual who (1) responds to beverage alcohol in a certain way, perhaps physiologically determined, by experiencing intense relief and relaxation, and who (2) has certain personality characteristics, such as difficulty in dealing with and overcoming depression, frustration, and anxiety, and who (3) is a member of a culture in which there is both pressure to drink and culturally induced guilt and confusion regarding what kinds of drinking behavior are appropriate, is more likely to develop trouble than will most other people.»

Maybe, just maybe, the problem with that model has something to do with the idea that the model breaks down when an increasingly large segment of the culture decides it is done with church.

We must be sensitive to the experience of men in other cultures and the models they use to interpet their experience; we must avoid the theological imperialism to which preoccupation with doctrines, along with literalism in interpretation, have often led.

But our culture longs for models of human excellence that extend far beyond mere technical competence and that temper the pride of intellect with wisdom and charity.

Looking primarily to models based on quantitative research methodologies to provide a clear direction for policy in regulating media and violence can also distract policy makers from coming to grips with other difficult but more important value questions that impinge on the issue of media and violence, such as the purpose of broadcasting, issues of ownership and control of media, the international context of Australian media, the dominant economic nature of most of Australia's social communications, the distinctive ways in which the media reproduce and reconstruct myths and symbols of violence from within the culture, and how audiences use and respond to media myths and symbols.

Parents spend most time with their children, parents create the culture at home, parents are the primary model of godliness, and parents are meant to teach their children.

Operating under the core philosophies of 80/20 business processes, customer - back innovation and a decentralized entrepreneurial culture, ITW's seven industry - leading segments leverage the ITW business model to generate solid growth with best - in - class margins and returns in markets where highly innovative, customer - focused solutions are required.

Time for some brutal honesty... this team, as it stands, is in no better position to compete next season than they were 12 months ago, minus the fact that some fans have been easily snowed by the acquisition of Lacazette, the free transfer LB and the release of Sanogo... if you look at the facts carefully you will see a team that still has far more questions than answers... to better show what I mean by this statement I will briefly discuss the current state of affairs on a position - by - position basis... in goal we have 4 potential candidates, but in reality we have only 1 option with any real future and somehow he's the only one we have actively tried to get rid of for years because he and his father were a little too involved on social media and he got caught smoking (funny how people still defend Wiltshire under the same and far worse circumstances)... you would think we would want to keep any goaltender that Juventus had interest in, as they seem to have a pretty good history when it comes to that position... as far as the defenders on our current roster there are only a few individuals whom have the skill and / or youth worthy of our time and / or investment, as such we should get rid of anyone who doesn't meet those simple requirements, which means we should get rid of DeBouchy, Gibbs, Gabriel, Mertz and loan out Chambers to see if last seasons foray with Middlesborough was an anomaly or a prediction of things to come... some fans have lamented wildly about the return of Mertz to the starting lineup due to his FA Cup performance but these sort of pie in the sky meanderings are indicative of what's wrong with this club and it's wishy - washy fan - base... in addition to these moves the club should aggressively pursue the acquisition of dominant and mobile CB to stabilize an all too fragile defensive group that has self - destructed on numerous occasions over the past 5 seasons... moving forward and building on our need to re-establish our once dominant presence throughout the middle of the park we need to target a CDM then do whatever it takes to get that player into the fold without any of the usual nickel and diming we have become famous for (this kind of ruthless haggling has cost us numerous special players and certainly can't help make the player in question feel good about the way their future potential employer feels about them)... in order for us to become dominant again we need to be strong up the middle again from Goalkeeper to CB to DM to ACM to striker, like we did in our most glorious years before and during Wenger's reign... with this in mind, if we want Ozil to be that dominant attacking midfielder we can't keep leaving him exposed to constant ridicule about his lack of defensive prowess and provide him with the proper players in the final third... he was never a good defensive player in Real or with the German National squad and they certainly didn't suffer as a result of his presence on the pitch... as for the rest of the midfield the blame falls squarely in the hands of Wenger and Gazidis, the fact that Ramsey, Ox, Sanchez and even Ozil were allowed to regularly start when none of the aforementioned had more than a year left under contract is criminal for a club of this size and financial might... the fact that we could find money for Walcott and Xhaka, who weren't even guaranteed starters, means that our whole business model needs a complete overhaul... for me it's time to get rid of some serious deadweight, even if it means selling them below what you believe their market value is just to simply right this ship and change the stagnant culture that currently exists... this means saying goodbye to Wiltshire, Elneny, Carzola, Walcott and Ramsey... everyone, minus Elneny, have spent just as much time on the training table as on the field of play, which would be manageable if they weren't so inconsistent from a performance standpoint (excluding Carzola, who is like the recent version of Rosicky — too bad, both will be deeply missed)... in their places we need to bring in some proven performers with no history of injuries... up front, although I do like the possibilities that a player like Lacazette presents, the fact that we had to wait so many years to acquire some true quality at the striker position falls once again squarely at the feet of Wenger... this issue highlights the ultimate scam being perpetrated by this club since the arrival of Kroenke: pretend your a small market club when it comes to making purchases but milk your fans like a big market club when it comes to ticket prices and merchandising... I believe the reason why Wenger hasn't pursued someone of Henry's quality, minus a fairly inexpensive RVP, was that he knew that they would demand players of a similar ilk to be brought on board and that wasn't possible when the business model was that of a «selling» club... does it really make sense that we could only make a cheeky bid for Suarez, or that we couldn't get Higuain over the line when he was being offered up for half the price he eventually went to Juve for, or that we've only paid any interest to strikers who were clearly not going to press their current teams to let them go to Arsenal like Benzema or Cavani... just part of the facade that finally came crashing down when Sanchez finally called their bluff... the fact remains that no one wants to win more than Sanchez, including Wenger, and although I don't agree with everything that he has done off the field, I would much rather have Alexis front and center than a manager who has clearly bought into the Kroenke model in large part due to the fact that his enormous ego suggests that only he could accomplish great things without breaking the bank... unfortunately that isn't possible anymore as the game has changed quite dramatically in the last 15 years, which has left a largely complacent and complicit Wenger on the outside looking in... so don't blame those players who demanded more and were left wanting... don't blame those fans who have tried desperately to raise awareness for several years when cracks began to appear... place the blame at the feet of those who were well aware all along of the potential pitfalls of just such a plan but continued to follow it even when it was no longer a financial necessity, like it ever really was...

he does not understand football culture...... and business......... his model so far has not won any trophies with the exception of the FA cup........

In answer to the concerns regarding the co-opting of Midwifery Care by the university model of education and practice, which threatens to create a single mono - culture of birth, we describe a legally sanctioned and protected means of practicing birth - care and midwifery with families in the private sector.

Corporate culture, the philosophy of imbuing employees with a set of higher company values that motivate them to work beyond the next pay cheque, was popular with US management in the 1980s, themselves inspired by the successful model of Japanese corporations.

The mechanistic modelling, treatment of people as resources, obsession with the short - term, and management by targets in the public sector are all symptoms of the sick ideology that has driven management culture, which Simon brilliantly dissected.

Evidence supporting minimum pricing is mixed, based solely on economic modelling and experiences in other countries with different drinking cultures.

With our human gut - on - a-chip, we can not only culture the normal gut microbiome for extended times, but we can also analyze contributions of pathogens, immune cells, and vascular and lymphatic endothelium, as well as model specific diseases to understand complex pathophysiological responses of the intestinal tract.»

The social stigma of entering a male - dominated field with a macho culture, the fear of intimidation and discrimination, and the lack of mentors and role models in positions of power are commonly cited reasons for women exiting or failing to enter the engineering workforce.

The paper identifies three main aspects of that masculine culture: stereotypes of the fields that are incompatible with how many women perceive themselves, negative stereotypes about women's abilities and a dearth of role models.

A common model says that people encountering a new culture go through highs and lows, with a honeymoon period in which differences are exciting, followed by phases of culture shock and adjustment before mastering the new culture (Black et al., The Academy of Management Review 16, 291 (1991); bit.ly / 1t9TRhw).

«Climate science is a «data - heavy» discipline with many intellectually interesting questions that can benefit from computational modeling and prediction,» said Dovrolis, a professor in the School of Computer Science, «Cross-disciplinary collaborations are challenging at first — every discipline has its own language, preferred approach and research culture — but they can be quite rewarding at the end.»

In 2016, the U.S. National Cancer Institute launched a scheme to develop more than 1000 cell culture models, including organoids, for researchers around the world to use, together with Cancer Research UK in London, the Wellcome Trust Sanger Institute in Hinxton, U.K., and HUB.

Existing cell culture models were not very realistic, Tuveson says, and creating genetically engineered mice took up to a year, compared with up to 3 weeks for pancreatic cancer organoids.

It brings together the author's work on the southern coast of Peru and, by mixing the results of excavation with ethnographic analogy, presents a model of Nasca culture that adds significantly to our understanding of the complex societies in the Andes.

Fiumera works in vivo with fruit flies while Mahler works in vitro using a 3 - D cell - culture model of the gastrointestinal (GI) tract to understand how ingesting nanoparticles influences glucose processing and the gut microbiome.

To model Gulf War Illness, the researchers treated cultures of human and rat neurons with an organophosphate called diisopropyl flurophosphate, which is an analog of sarin.

And finally, you can personality style model to determine whether or not your preferred style will fit with a given company's culture.

Those doses were chosen in analogy with the prion field, in which it is very common to observe that 1 % and 0.1 % tissue homogenate containing prion protein aggregates is able to induce pathological changes both in cell culture experiments and in in vivo animal models.

These models include in vitro experiments with purified recombinant or synthetic proteins, cell culture experiments, and infectivity studies with Tg mice expressing the appropriate form of the protein.

Mouse embryonic stem cells stained for key pluripotency markersGRAZIANO MARTELLO Combining computer science algorithms with biological data has enabled researchers to create a model of the minimal number of factors necessary for mouse embryonic stem cells (ESCs) to self - renew in culture.

Consisting of optimized media and reagents, MimEX ™ Tissue Model Systems provides an alternative to current 3 - D cell culture modes, such as organoids, with the added benefit of...

We exploit chick and mouse embryo animal models, combined with live imaging, cell and tissue cultures and molecular approaches.

Utilizes spontaneous and CRISPR / Cas9 generated mouse lines along with primary cell culture models to look at the molecular intersection between the motor neuron and heart phenotypes in mouse models of Spinal Muscular Atrophy with Respiratory Distress (SMARD).

7/16/2008 Improved Culture System for Hepatitis C Virus Infection A University of California, San Diego School of Medicine researcher has developed the first tissue culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible... Culture System for Hepatitis C Virus Infection A University of California, San Diego School of Medicine researcher has developed the first tissue culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible... culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible... More...

To address these different topics we are developing relevant animal models that will be used in combination with primary neuronal cultures, rodent brain slices, and brain tissues.