But while researchers have managed to
culture other cell types, they have failed to grow the key dopamine cells needed by Parkinson's sufferers (This Week, 5 August).
Not exact matches
Also, researchers could carefully select which blood
types to
culture with each batch of stem
cells, creating stockpiles of needed blood products for people with extremely rare blood
types whose blood
cell makeup makes it challenging to find good blood matches for transfusions because they would reject most
other types of blood.
Cultures representing two
other hereditary liver diseases, alpha 1 — antitrypsin deficiency (a protein - folding disorder that leads to
cell death and liver failure) and glycogen storage disease,
type 1a (in which a liver enzyme deficiency impairs the body's glucose metabolism), also displayed disorder - specific abnormalities.
Her team decided to try a
cell - growing approach, called 3D
cultures, that's been successful for
other types of
cells that need to form complex structures as they grow.
Next, the team used
other mouse models in which part of the lung was removed and single
cell culture to study the plasticity of
cell types during lung regrowth.
By comparing hippocampal and cortical neurons in mono -
culture (with
other cells of the same
type) and in co-
culture (both
cell types deposited within one device), the research showed that some features from hippocampal
cells, like the percentage of action potential spikes found in bursts, were significantly higher when
cultured together with cortical
cells.
Using
cultured cells derived from human tumors of the breast and prostate gland, they confirmed that the IL6R / STAT3 / miR -34 a feedback loop is also activated in
other tumor
types.
Next, the researchers would like to investigate how to
culture the
other types of progenitor
cells that are required for a full kidney, in addition to the nephrons formed by NPCs.
Haruko Obokata of the RIKEN Center for Developmental Biology (CDB) in Kobe, Japan, and colleagues at
other Japanese institutions and at Harvard Medical School in Boston reported that simply subjecting blood
cells from newborn mice to a moderately acidic environment for 25 minutes and then tweaking
culture conditions could generate pluripotent stem
cells capable of developing into nearly all of a body's
cell types.
In addition, the molecular beacons technique http://www.lependart.com could have broad applications across regenerative medicine, because it could be used with
other types of
cells produced from stem
cell cultures, such as brain
cells or insulin - producing islet
cells.
«In the future, this will move us towards a way to understand how to generate a cardiac muscle or
other specific
cell type without having to try an unwieldy number of
cell culture conditions.»
Our Intestine - Chip also allows researchers to
culture intestinal epithelial
cells alongside
other cell types, such as immune
cells, and analyze how these different
cell types interact.
Type 2 diabetic
cells exposed to 1 μmol / l insulin expressed a basal glucose transport activity similar to corresponding control
cultures and significantly greater than the basal glucose transport activity seen under the
other insulin conditions (P < 0.05).
Culturing pluripotent stem cells, including embryonic stem cells, is much more complicated and expensive than culturing most other ce
Culturing pluripotent stem
cells, including embryonic stem
cells, is much more complicated and expensive than
culturing most other ce
culturing most
other cell types.
This is basically tweaking the molecules: making small chemical changes to the compound in hopes of finding something that could block the growth of blood vessel
cells initially in the
culture dish without having toxic effects on
other cell types.
Similar to primary keratinocytes, long - term —
cultured squamous
cell carcinoma (30) and many
other epithelial cancer
cells (30, 31) can also form different
types of clones in
culture.