Sentences with phrase «culture system»

As a result, 3D cell culture systems have become a staple of cell biology.

Now, a combination of innovative 3D culture systems, automated image analysis, and sophisticated microscopic shape mapping is driving a rush of groundbreaking discoveries.

Using her new culture system, she joined forces with colleagues to research which cells in an embryo contribute to which parts of the adult animal, a process called fate - mapping.

A materials scientist could produce culture systems with different mechanical properties.

Using this special culture system, they were able to test potential new cancer drugs.

To investigate how the liver responds to bile accumulation, the research team used an artificial culture system, which allowed the easy manipulation of cultured liver cells.

This study used a model cell culture system that represents what happens in an animal or human.

CNHS began using the Kickboard school culture system in July 2013.

To support teachers in implementing the Student Motivation System, Durham Elementary began using the Kickboard school culture system in fall 2015.

Therapeutic applications of CRISPR - Cas gene editing are being advanced with the goals of finding cures and treatments for a range of serious diseases, developing needed medicines for both household pets and production animals, and improving cell culture systems for bioproduction.

Many theologians of the sects continued to talk as if they were the exponents of the normative culture system of the commonwealth, while actually they represented only that of, at best Christianity in general, at worst their exclusive sect.

The technology also improves cell culture systems used to produce therapeutic proteins, vaccines, and gene therapy vectors.

Helicobacter pylori induces hyperproliferation in a three - dimensional culture system in conjunction with up - regulation of ß - catenin target genes.

First, cells from Cellartis Human iPS Cell Line 22 (ChiPSC22) were modified to stably express AcGFP1, then these cells were cultured using the DEF ‑ CS culture system in a 48 - well plate.

While infection of mice with B. burgdorferi recovered from any monkey (treated or untreated) was not generally productive, the recovery by xenodiagnosis and through the use of an in vivo culture system, of intact spirochetes transcribing RNA indicates that the persistent spirochetes recovered post-treatment are of comparable viability to those recovered from untreated primates.

«An important, overarching goal of the field is to develop culture systems using primary cells with minimal ex vivo [external] manipulation.

However, it is practically difficult to perform the rescue experiments in the organoid culture system because the lentivirus transfection is required for the gene transduction into the primary stem / progenitor cells and the APC gene (> 8.5 k base pairs) is too large to be cloned into the lentivirus.

They simulated normal testicular development in each of these species using a novel in vitro culture system called FeTA.

This hydroponic starter kit from PowerGrow uses the Deep Water Culture system with four 5 - gallon buckets that are FDA - approved.

Successful single - cell cloning is achieved using our monolayer - based culture system, which bypasses the challenges of colony - based culture by allowing single - cell passaging, promoting survival of clones, and supporting further clonal expansion.

The cells were then grown for nine days according to the Cellartis DEF ‑ CS 500 Culture System User Manual.

RBM also offers innovative and proprietary ex vivo testing systems such as TruCulture ™, the first fully - closed, reproducible whole blood culture system.

A unique combination of technology and personalized leadership coaching, the Kickboard school culture system helps educators streamline and simplify behavior management and interventions, positive behavior reinforcement, classroom management, social and emotional learning, and district - wide school culture analysis.

«3 - D culture system for pancreatic cancer has potential to change therapeutic approaches.»

The project included upgrading the process water system, starter culture system, clean - in - place plant, overflow protection device pre-press and mould filling unit.

«Our application of this technology is powerful because it allows us to identify specific neural stem cell defects that are invisible in the cell culture systems typically used by brain scientists.

These so - called endometrial organoids promise to shed light onto the processes that occur during the monthly menstrual cycle and open up the possibility of studying diseases of the uterus, such as endometrial atrophy (thinning of the lining) or cancer, in a lab culture system.

By screening a library of 780 Food and Drug Administration approved therapeutics, Chopra, Jourdan Andersson, a graduate student at UTMB, and others on the research team were able to identify as many as 94 drugs that were significantly effective in a cell - culture system when tested against Yersinia pestis, the bacteria that cause the plague and which is becoming antibiotic resistant.

«As bioengineers, we can now design 3D culture systems where environmental parameters such as composition, porosity, and stiffness can be precisely tuned to study the importance of these cues on tumorigenesis,» says coauthor Sandeep Koshy, a Harvard graduate student in the Harvard - MIT Program in Health Sciences and Technology, who works in Mooney's lab at Harvard SEAS and at the Wyss Institute for Biologically Inspired Engineering.

This unique culture system has great potential for future salivary gland research and for the development of new cell - based therapeutics.»

Beddington solved the problem by adapting a rat culture system for use in mice.

In a novel application of human induced - pluripotent stem cell (iPSC) technology, the team generated powerful culture systems that represent different areas of the brain.

The cell culture system described here provides, for the first time, a means with which to perform controlled detailed examinations on both the activated and differentiated phenotype of organ - specific microvascular endothelial cells.

AHERF Neurosciences Grant (G9410 -020-Y01)- Co-PI; «Differential expression and sorting of the neuron - specific class III b - tubulin isotype in human neuronal and neuroendocrine tumor cell lines maintained in an organ culture system».

The sperm culturing system will allow researchers to further explore the basic biology of sperm production in vertebrates.

Cellartis human iPS cells from the ChiPSC22 line (Figure 2) and the ChiPSC18 line (Figures 3 — 7 and Table I) were grown in the Cellartis DEF ‑ CS 500 Culture System before editing.

Dr. Kay Elder, study co-author from the Bourn Hall Clinic, says: «Successful IVF treatment is crucially dependent on culture systems that provide an optimal environment for healthy embryo development.

The DEF - CS system is a robust culture system for efficient expansion of human induced pluripotent stem (iPS) cells in a feeder - free and defined environment.

These results provide the validity to the newly developed hypoxia / reoxygenation culture system for examining the regulation of CSCs in breast cancer cell lines by niche factors in the tumor microenvironment and developing differential targeting strategies to eradicate breast CSCs.

The Liver - Chip showed improved viability and hepatic function compared to conventional hepatocyte culture systems over long - term culture.

This protocol is used for general maintenance and passaging of hES and iPS cells in a feeder - independent culture system such as mTeSR1 / Matrigel.

To delineate the molecular mechanism, a reproducible culture system for iPS cell derivation is critical.

Although estimates citing the exact quantities of viral vectors required to meet clinical demand vary (26), developers are increasingly moving away from small - scale operations and choosing to operate larger - scale apparatus such as stainless steel or single - use bioreactor culture systems (4, 27).

Regardless of whether the gene expression changes are deterministic or random, feedback between cell types may help to stabilize this heterogeneous culture system.

These platforms are currently being evaluated by the Food and Drug Administration (FDA) as a tool to more effectively study the effects of potential chemical and biological hazards found in foods, cosmetics or dietary supplements than existing culture systems or animal models.

Exposure of the epithelial monolayer to an apical fluid shear stress (0.2 dyne cm 2) that mimics that found in living kidney tubules results in enhanced epithelial cell polarization and primary cilia formation compared to traditional Transwell culture systems.

An ex vivo organotypic culture system was used to examined exposure effects at the time of fetal testosterone production initiation at GD14.5.