Dr. Huizing demonstrated that elimination of the single mutant allele using a synthetic small interfering RNA (siRNA) rescued the abnormal phenotype in
cultured cells from sialuria patients.
The Krainer team, in collaboration with a team at Isis Pharmaceuticals, surveyed a large number of antisense oligonucleotides (ASOs) and found that some of these ASOs are able to correct the mRNA splicing defect in
cultured cells from SMA patients.
Hendrik is preparing the publication of the most complete woolly mammoth genome yet, and Harvard geneticist George Church's team is already working to introduce specific DNA variants — genes for hair, tusks, subcutaneous fat and cold resistance — into
cultured cells from Asian elephants (right).
The two French scientists
cultured cells from lymph nodes of patients.
At the meeting, team member Koffi Konan, a plant molecular biologist, showed how the plants were made by inserting shortened or backward versions of each of the genes — Ara h1, Ara h2, and Ara h3 — into
cultured cells from peanut plants.
To find out, the researchers injected a cloned telomerase gene into
cultured cells from retina, skin, and blood vessels, all of which are associated with degenerative, aging - related diseases.
Researchers from Duke University had previously used CRISPR to correct genetic mutations in
cultured cells from Duchenne patients, and other labs had corrected genes in single - cell embryos in a laboratory environment.
Not exact matches
One habit of Prince's they told me about struck me as so counter to our times that I came to see it as illustrating what set him apart
from today's
culture of celebrity: he allowed no one near him to use a
cell phone.
Based on a 3D image such as an MRI scan, Aspect's machine builds relatively complex organic structures out of a «hydrogel» embedded within
cells taken
from the body and grown in a
cell culture.
Animal
cells are
cultured from stem
cells and incubated in a «bioreactor» into tissue that can be «harvested» and formed into familiar foods like meatballs, patties, and fish sticks.
Post, of MosaMeat, who created the first hamburger
from cultured animal
cells in 2013 with backing
from Google billionaire Brin, believes some of his competitors have set unrealistic timelines to market in part because that's what tech investors want to hear.
Cultured meat producers still have to source the first set of
cells from an animal — even if it's just a small biopsy that doesn't require slaughter.
GFI's scientists have identified the critical aspects of clean meat production,
from the
culturing of the initial
cells all the way to distribution.
Rather than obtaining meat
from animals raised on environmentally destructive factory farms and slaughtered in filthy slaughterhouses, clean meat is produced by taking a small sample of animal
cells and replicating them in a
culture outside of the animal.
If I have a bunch of
cells from a throat
culture or other medical swab, that isn't a human life.
Embryos are different
from mere
cell cultures in a number of important ways.
In both cases individual members may exercise some dominance over others, in particular by altering the patterns guiding further growth and development, but the social coordination stems
from basic patterns embodied in the genetic makeup of the plant
cells and in the laws and traditions of human
culture.
A
cell in my brain is different
from a
cell not in my brain but, say, in a
culture of
cells in a dish.
While some still object to
cells being taken
from animals and used by scientists to grow clean meat in laboratories — and some just don't like the idea of eating a «
cultured» steak created by men and women in white coats — others see the lab - grown meat revolution as key to solving the environmental crisis linked to meat eating.
Rather than obtaining meat
from animals raised on environmentally destructive factory farms and slaughtered in filthy slaughterhouses, clean meat is produced by taking a small sample of animal
cells and replicating them in a
culture outside of the animal.
The researchers experimented with inducing oxidative stress in a human
cell line
culture with and without VCOP (virgin coconut oil polyphenols) to observe how VCOP positively promoted catalase, a very important enzyme in protecting the
cell from oxidative damage, and glutathione (GSH), a self - recycling antioxidant produced by the liver.
Tyson Ventures, the venture capital arm of Tyson Foods, Inc., has invested in food tech startup Memphis Meats, a leader in
cultured meat produced directly
from animal
cells.
In 2010, researchers
from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem
cells in mice and in lab
cultures, and it also prevented the growth of new tumor
cells.
Transient Silencing of 14 -3-3sigma promotes proliferation of p63 - positive progenitor
cells isolated
from human breastmilk in mammary epithelial
cell culture.
While scientists have previously had success in 3D printing a range of human stem
cell cultures developed
from bone marrow or skin
cells, a team
from Scotland's Heriot - Watt University claims to be the first to print the more delicate, yet more flexible, human embryonic stem
cells (hESCs).
The team took small pieces of ear tissue
from XXY and XYY mice,
cultured them, and collected connective tissue
cells known as fibroblasts.
The next step, Silber says, will be harvesting stem
cells from around a «spermless» man's testicles, introducing them into
cultures where the
cells multiply, and then reimplanting those
cells in the man's testicles, which then nurture them into fully mature sperm - producers.
The team tested whether overexpression of PGC1 - alpha could protect
cultures of rat brain
cells from the pesticide rotenone, which inhibits complex I of the electron transport chain in neuronal mitochondria and produces many symptoms similar to those of Parkinson's.
The most promising chemical — sulforaphane, a naturally occurring compound found in cruciferous vegetables — tamped down glucose production by liver
cells growing in
culture, and shifted liver gene expression away
from a diseased state in diabetic rats.
«Our review brings together published literature and laboratory records
from early research into GALV which is a known contaminant of laboratory
cell culture.
The scientists also showed, in lab -
cultured human
cells, that an ALDH - blocking drug strips regulatory T -
cells of their ability to grow and protect themselves
from cyclophosphamide.
In addition, they found that PD - L1 blockade increased virus production in the
cell culture from such patients.
It's almost impossible to
culture naked mole rat
cells in the lab, which made Andrei Seluanov and Vera Gorbunova
from Rochester University, New York, wonder if this might be linked to their ability to resist cancer.
A team spearheaded by Dr. Markus Helfer and Prof. Dr. Ruth Brack - Werner
from the Institute of Virology and Prof. Dr. Philippe Schmitt - Kopplin
from the Analytical BioGeoChemistry research unit (BGC) performed a detailed investigation of the effects of PS extracts on HIV - 1 infection of
cultured cells.
Potti and his colleagues began by testing chemotherapy drugs on
cultured cell lines
from human tumors, such as
from the lung, breast, or ovary.
Now researchers at the University of Plymouth, working in partnership with pharmaceutical company AstraZeneca, have for the first time successfully
cultured and maintained
cells from the guts of rainbow trout, a recommended fish species for toxicological studies.
Since the algae reproduces by
cell division about once per day in the laboratory, numerous genetically identical
cultures could be derived
from the isolate.
Permafrost had preserved tissue
from one species — a narrow - leafed campion plant — exceptionally well, so researchers at the Russian Academy of Sciences recently decided to
culture the
cells to see if they would grow.
Some of the leading non-animal tests are conducted on
cell cultures, human and animal corneas
from eye banks, corneal tissue
cultures, and frozen corneas supplied by hospitals.
New developments include reaction systems for catalysis research, sampling
from reactors, systems for high - throughput applications in synthesis, the handling of microorganisms or
cell -
culturing procedures, and more.
The company isolates,
cultures and processes adult stem
cells from a patient's bone marrow or synovial fluid.
One would
culture thin sheets of meat, seeded by
cells from a living animal, on a reusable polymer scaffold; the other would grow meat on small edible beads that stretch with changes in temperature.
High levels of the protein were also found in
cultures of metastatic
cells from tumours of the colon, breast, head and neck.
By analyzing chemical changes of the IRS - 2 protein in immortalized
cultures of human white blood
cells, it determined that IRS - 2 appeared in two different forms — «on,» which allows the signal to pass through, and «off,» which stops the signal
from activating the
cells into M2 macrophages.
For example,
cultured cells exhibit rhythmic oscillations in gene expression where there is no input
from the master clock.
The
cells used to build the organs could be
cultured from stem
cells taken
from fat or bone - marrow tissue, he says: «We could engineer a blood vessel
from your own
cells.»
What he showed is if he took the fluids
from cultures of
cells that lit up and squirted them on
cells that were at a low
cell density, they all turned on light.
As a graduate student at Princeton University, Moshe Pritsker tried in vain to grow a
culture of embryonic stem
cells from instructions laid out in the methods section of a journal article.
In other experiments, the protein blocked the virus
from infecting
cells in
culture, and it even prevented mice
from getting sick when administered either 1 day before or after viral exposure, they report today in Nature Biotechnology.
In cloning procedures generally, nuclei are extracted
from cultured cells that might have come originally
from an embryo, a fetus or an adult organism.