To test the suitability of guanabenz as a potential treatment for MS, Popko and his team exposed
cultured oligodendrocyte cells to interferon gamma — a molecule that increases inflammation — resulting in greatly increased myelin loss and cell death.
Not exact matches
Finally, they demonstrated that zebrafish OPCs differentiate into mature
oligodendrocytes when
cultured together with human motor neurons, differentiated from induced pluripotent stem cells.
Oligodendrocyte differentiation was induced by
culturing the cells in DMEM / F12, 1 % N2, and IGF - 1 (200 ng / ml).