Using a technique that introduces tiny wrinkles into sheets of graphene, researchers from Brown University have developed new textured surfaces for
culturing cells in the lab that better mimic the complex surroundings in which cells grow in the body.
They cultured the cells in the lab for a day, then exposed them for 3 days to a virus which contained the normal gene for the receptor.
The team collected two small skin samples from each, and then
cultured the cells in the lab and inserted the gene that makes fireflies glow into the gene that regulates the cells» clock.
Not exact matches
While some still object to
cells being taken from animals and used by scientists to grow clean meat
in laboratories — and some just don't like the idea of eating a «
cultured» steak created by men and women
in white coats — others see the
lab - grown meat revolution as key to solving the environmental crisis linked to meat eating.
In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cell
In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study
in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cell
in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem
cells in mice and in lab cultures, and it also prevented the growth of new tumor cell
in mice and
in lab cultures, and it also prevented the growth of new tumor cell
in lab cultures, and it also prevented the growth of new tumor
cells.
Researchers hope the organoids will be better than
lab animals or
cells growing
in culture at revealing how the human brain develops, both normally and when things go awry, and identify potential therapeutic or genome - editing targets.
She was always ready to learn new techniques, and she diversified her skill set by working
in the animal facility,
cell culture room, and also
in a mass spectrometry
lab.
Culturing stem
cells by day, and audiences
in dingy stand - up clubs by night, it wasn't until Helen Pilcher left the
lab that she started basing her comedy on science.
Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to
labs for use
in experiments, helped clear HSV - 1 infection
in cultured human corneal
cells,
in donated human corneas, and
in the corneas of mice infected with HSV - 1.
They found high levels of the regulatory T -
cells in patients treated with post-transplant cyclophosphamide, and
lab -
cultured cells survived cyclophosphamide treatment.
Researchers from Duke University had previously used CRISPR to correct genetic mutations
in cultured cells from Duchenne patients, and other
labs had corrected genes
in single -
cell embryos
in a laboratory environment.
Cultured in the
lab, the changed
cells showed an ability to differentiate into (or become) two discrete
cells found
in breast tissue.
Years ago W.U.'s Holtzman and former colleague Marc Diamond, who has since moved to the University of Texas Southwestern Medical Center, identified tau - binding antibodies that slow the spread of toxic tau clusters
in a
lab assay using
cultured cells.
Still, only a few dozen
labs in the world are certified as BSL4 facilities; some are very small and only work on diagnostics, or
cell cultures, or a single species of animals.
The scientists also showed,
in lab -
cultured human
cells, that an ALDH - blocking drug strips regulatory T -
cells of their ability to grow and protect themselves from cyclophosphamide.
It's almost impossible to
culture naked mole rat
cells in the
lab, which made Andrei Seluanov and Vera Gorbunova from Rochester University, New York, wonder if this might be linked to their ability to resist cancer.
A prototype device built by nScrypt, a company
in Orlando, Florida, deposits one - hundredth - of - an - inch - thick dollops of
lab -
cultured cells onto a layer of gel - based paper invented at the University of Utah.
In studies with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication in cultures of cells grown in the la
In studies with human fibroblasts that make up connective tissue, Boger's team tested whether NOD1 activity could affect CMV replication
in cultures of cells grown in the la
in cultures of
cells grown
in the la
in the
lab.
Zheng, together with Leah Boyer, then a researcher
in Gage's
lab and now director of Salk's Stem
Cell Core, generated diseased neurons by taking skin
cells from patients with Leigh syndrome, reprogramming them into stem
cells in culture and then coaxing them to develop into brain
cells in a dish.
In the lab, the herbicide 2,4 - dichlorophenoxyacetic acid (sold as weed killer and called 2,4 - D) can prompt cells in culture to elongate, build a new cell wall, and start dividing to form embryo
In the
lab, the herbicide 2,4 - dichlorophenoxyacetic acid (sold as weed killer and called 2,4 - D) can prompt
cells in culture to elongate, build a new cell wall, and start dividing to form embryo
in culture to elongate, build a new
cell wall, and start dividing to form embryos.
At the Galveston National Laboratory, which houses a biosafety level 4
lab, researchers shut down experiments, euthanized infected animals, put pathogens
in cold storage, and autoclaved
cell cultures.
In collaboration with Ding, the lab of Olivier Voinnet at the Swiss Federal Institute of Technology in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
In collaboration with Ding, the
lab of Olivier Voinnet at the Swiss Federal Institute of Technology
in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
in Zurich also reported
in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
in an accompanying paper the detection of viral siRNAs
in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
in cultured mouse embryonic stem
cells infected by the Encephalomyocarditis virus.
In addition to emphasizing the recruitment of graduate students, American universities have a number of on - campus service facilities such as modern research
labs, well - stocked reagent rooms, and
cell culture facilities.
The implications were hardly lost on the Bethesda crowd: If the virus was transmitted
in cell cultures in Ruscetti's
lab, it could also be contaminating the nation's blood supply as a result of blood donations from unknowingly infected donors.
Though Li's adhesive has been tested only
in human
cell cultures and
in lab animals, another bio-inspired glue has made its way into human trials.
«First we established an efficient method for
culturing dinoflagellate
cells in our
lab,» said Shinichiro Maruyama, an assistant professor at Tohoku University.
Six years ago, Dr. Monje started to create and share
cell cultures of patients» DIPG
cells that could be studied
in labs.
Cantley's
lab and collaborators found that large doses of vitamin C did indeed kill
cultured colon cancer
cells with BRAF or KRAS mutations by raising free radical levels, which
in turn inactivate an enzyme needed to metabolize glucose, depriving the
cells of energy.
When the researchers applied some of these
cultures to mouse colon
cells in the
lab dish, the
cells were stimulated to release PYY hormone.
The microbes rely on oxygen, carbon and other nutrients
in their deep environment to live, but Røy's team found that carbon is so limited that the
cells respire oxygen 10,000 times slower than bacteria
in lab - grown
cultures.
At the time,
culturing stem
cells was notoriously hard, but after combing through previous
lab experiments, another postdoc
in Clevers's
lab, Toshiro Sato, concocted a mix of growth factors that coaxed the gut stem
cells to replicate
in a dish.
Set up experiments for whole week: Start
cell cultures, book microscopes, make buffers, and even find time over the bacterial incubator for a spot of eyelash fluttering at the sexy postdoc
in the
lab next door.
This is the first time these pathways have been studied
in live mosquitoes with dengue virus, although similar studies have been conducted under controlled conditions using
cells cultured in the
lab.
Wagers, then a postdoctoral fellow
in the Stanford University
lab of stem
cell biologist Irving Weissman, spent a week
in Verfaillie's
lab in 2002 trying to learn to
culture MAPCs.
Pure darcin, produced
in cell culture in the
lab, elicited the same reaction, the authors report online today
in Science.
The scientists say their gadget provides a quicker diagnosis that today's typical method,
in which a
cell sample is taken and
cultured in the
lab to look for the presence of the Candida albicans fungus.
Traditionally,
cell culture in the
lab has been done
in petri dishes and on other flat surfaces.
The inhibition of Rac1 also led to
cell death
in mouse lungs
cultured in the
lab.
The patient, already
in a wheelchair, visited the
lab and watched
in amazement as his own muscle
cells beat
in a
culture dish after corrective editing.
Cells from her malignancy were
cultured and used to start a
cell line, called HeLa, which lives on to this day
in research
labs around the world.
Salk researchers created kidney progenitor
cells that survive
in the
lab using 3 - D
culture and a mix of supporting molecules.
When they knocked two of these genes out of the bacterium's genome, it couldn't survive
in a
lab culture of immune
cells, they report
in the 26 May issue of Science.
Ralph Brinster, part of the team at the University of Pennsylvania
in Philadelphia that first
cultured sperm stem
cells in the
lab, has written that
culturing stem
cells from human sperm is not far off — humans and mice, like other mammals, he says, require similar growth factors.
The
cell cultures in the petri dishes are of human origin, and
in some aspects resemble human brains more than the brains of
lab animals such as rats or mice do.
Previous experiments from other
labs have successfully brought embryos more than 10 days into development by implanting them on a three - dimensional scaffold of endometrial
cells and nutrients
in culture.
An oral drug used to treat an illness unrelated to HIV eradicated infectious HIV - producing
cells in lab cultures while sparing uninfected
cells — and suppressed the virus
in patients during treatment and for at least eight weeks after the drug was stopped, according to results of a clinical pilot trial and researchers at Rutgers University and Dartmouth College.
Unlike many other stem
cell treatments, such as heart patches, the procedure Taylor and his colleagues used did not require any advance
culturing or growth
in the
lab.
Five days post-stimulation the anti-CD3 / anti-CD28 coated magnetic beads were removed from each of the three
cultures (non-transduced (NTD), AdX4 - ZFNs, and AdR5 - ZFNs) and 2.5 million
cells were seeded
in each of four
cultures that were subsequently infected with either Bk132 (primary X4 isolate), HxB2 (
lab - adapted X4 isolate), R3A (R5X4 primary isolate), or media only (mock).
COURTESY SHENDURE AND SCHIER
LABS CRISPR FOR FATE - MAPPING Researcher: Jay Shendure, Professor, Department of Genome Sciences, University of Washington Project:
In collaboration with Alexander Schier's lab at Harvard University, Shendure's group came up with a new way to trace cell lineages in cell culture and in whole organisms — in this case, developing zebrafis
In collaboration with Alexander Schier's
lab at Harvard University, Shendure's group came up with a new way to trace
cell lineages
in cell culture and in whole organisms — in this case, developing zebrafis
in cell culture and
in whole organisms — in this case, developing zebrafis
in whole organisms —
in this case, developing zebrafis
in this case, developing zebrafish.
«The region selective - state of these stem
cells is entirely novel for laboratory -
cultured stem
cells and offers important insight into how human stem
cells might be differentiated into derivatives that give rise to a wide range of tissues and organs,» says Jun Wu, a postdoctoral researcher
in Izpisua Belmonte's
lab and first author of the new paper.