The current phase of the study consists of a longitudinal follow - up of the 400 families who were randomized to treatment and control conditions and in which the mother and child were still alive and the family had not refused participation at earlier phases.
In
the current phase of the study, we are interviewing the original participants as the adopted children enter the early school - aged years.
Not exact matches
Based on results
of the
current study described in a report online June 18 in the journal Cancer Cell, Johns Hopkins researchers say they are planning a
phase I clinical trial to test the paclitaxel - fostamatinib combination therapy in patients with recurrent advanced ovarian cancer.
«The
current results do not exclude the possibility that the early dietary modification may affect the latter
phase, and therefore it is extremely important to continue to follow the
study participants into the final endpoint, which is the age
of ten years.
According to the
current schedule, it is envisaged that the drug candidate will be tested on humans as part
of a
phase 1
study in November 2017.
Illustrating the tricky path
current Alzheimer's research faces, the
study was published literally hours after giant pharmaceutical company Merck announced the cancellation
of a
Phase 3 clinical trial surrounding a drug that targets the exact same enzyme.
According to Col Jerome Kim, Walter Reed Army Institute
of Research, US, who was also part
of the lead group for the
study, apart from the
current four doses
of vaccines that were given to subjects in the
phase III clinical trials in Thailand, they are planning to give a booster does after six months to increase the strength
of the vaccine.
Table 1: Selection, Design & Construction
of HSV - based Oncolytic Viruses Table 2: Selection, Design & Construction
of Adenovirus - based Oncolytic Viruses Table 3: Selection, Design & Construction
of Vaccinia Virus - based Oncolytic Viruses Table 4: Selection, Design & Construction
of Vesicular Stomatitis Virus - based Oncolytic Viruses Table 5: Selection, Design & Construction
of Newcastle Disease Virus - based Oncolytic Viruses Table 6: Selection, Design & Construction
of Various Virus - based Oncolytic Viruses Table 7:
Current Company - Sponsored Clinical Trials
of T - Vec Table 8: Clinical Trials
of ColoAd1 Table 9: Clinical Trials with JX - 594 Table 10: Clinical Trials with GL - ONC1 Table 11: Clinical Trials
of CAVATAK (CVA21) Table 12: Clinical Trials with MV - NIS Table 13: Overview
of Oncolytic Viruses by Development
Phase & Virus Family Table 14: Profile
of Approved and Marketed Oncolytic Viruses Table 15: Pivotal
Study Design
of Oncolytic Viruses in Late Stage Development Based on Previous Clinical Results Table 16: Approved Indications
of Immune Checkpoint Inhibitors Table 17: Active Clinical
Studies of Oncolytic Viruses in Combination with Immune Checkpoint Inhibitors (ICI) Table 18: Planned Clinical
Studies of Oncolytic Viruses in Combination with Immune Checkpoint Inhibitors (ICI) Table 19: Active or Planned Clinical
Studies of Oncolytic Viruses in Combination with Other Anti-Cancer Therapeutics Table 20: Pattern
of Transgenes in Oncolytic Viruses in Relation to Development
Phase Tables 21a and 21b: Indications and Frquency and Way
of Administration
of Oncolytic Viruses in Active and / or Positive Completed Clinical
Studies Table 22: Small and Medium Pharma & Biotech as Partner for Regional Co-Development
of Oncolytic Viruses Table 23: Immuno - Oncology Portfolio
of Major Pharma & Biotech with Interest in Oncolytic Viruses Table 24: Interests
of Major Pharma & Biotech in Oncolytic Viruses Table 25: First Generation Oncology Virus Companies and their Sources
of Technology Table 26: Second Generation Oncology Virus Companies and their Sources
of Technology Table 27: Third Generation Oncology Virus Companies and their Sources
of Technology Table 28: Fourth Generation Oncology Virus Companies and their Sources
of Technology Table 29: Grants, Credits & Donations Table 30: Financing by Venture Capital, Private Equity and Other Private Placements Table 31: Collaboration & Licensing Agreements Table 32: Companies Listed on Stock Exchange & Offerings Table 33: Mergers & Acquisitions
Current practice is therefore based on findings from early -
phase and retrospective primary CNS lymphoma
studies, and extrapolations
of survival data among patients with systemic B - cell lymphoma, Dr. Doorduijn said.
The UT
study, which only deals with the extraction
phase of the natural gas supply chain, is the opening chapter in this broader scientific effort designed to advance the
current understanding
of the climate implications
of methane emissions resulting from the U.S. natural gas boom.
The difference with THIS
study is that they try hard to initialize it with an accurate representation
of the
current state
of the ocean, and therefore try to get the
PHASE of the PDO right, so they can attempt a prediction
of what will happen in the coming years.
This bipartisan bill directs the EPA to do a four -
phase study that 1) develops a universal definition
of black carbon; 2) identifies global black carbon sources and reduction technologies; 3) identifies
current and possible international funding opportunities to mitigate black carbon emissions; and 4) identifies opportunities for future research and development.
Future
studies should follow guidance on the development and evaluation
of complex interventions (such as the Medical Research Council's guidance).76 The results
of all
phases of intervention development also need to be published alongside trial results, as
current studies alone do not allow us to fully understand why interventions have not produced expected effects.
The size
of the CfC impacts on most outcomes was small, but can be considered positive relative to what was observed in the early
phase of the UK Sure Start evaluation.3 The
current results are also comparable in size to those found in the later impact evaluation
of the Sure Start programme, in which 3 - year - old children were exposed to mature SSLP throughout their entire lives.4 Reviews
of the effectiveness
of early childhood interventions have found that most
studies reported effect sizes on parenting and child outcomes that were small to moderate.14 15 When comparing CfC and SSLP with other interventions, it is important to remember that the evaluations
of these interventions measured effects on an entire population, rather than on programme participants, as is the case in the evaluation
of many other interventions.
Phase 4
studies, which characterize the
current state
of the field, are guided by complex multivariate models that focus on underlying mechanisms over time.