Sentences with phrase «cuts in a specific gene»
Early on, researchers realized they could use CRISPR - Cas9 to make single cuts in a specific gene pretty easily.
https://en.hdbuzz.net/ Not exact matches
The advance is based on a technique that allows scientists to narrow in on a specific gene and cut - and - paste bits of DNA to change its function, known as CRISPR - Cas9.
When Cas9 and the short guide RNA targeting a disease gene are delivered into cells, a specific cut is made in the genome, and the cells» DNA repair processes glue the cut back together, often deleting a small portion of the genome.
The disease is among many conditions that scientists are hoping to treat through the recently developed CRISPR - Cas9 gene - editing tool, in which an RNA strand guides an enzyme called Cas9 to cut a specific portion of DNA.
Wong and his team then inserted another gene in the same cell that made a modified recombinase, activated only when bound to a specific drug; without it, the recombinase wouldn't cut the DNA.
Chen, also an expert in the processes by which genes are turned on and off, has pioneered cutting - edge organoid systems that recreate prostate tumors and will allow the team to much more easily test the activity of various drugs against tumors with specific mutations.
In a groundbreaking study recently published in the journal PLOS One, the scientists used a pair of engineered proteins to cut DNA in a site - specific manner to disrupt a targeted gene in the mosquito genomIn a groundbreaking study recently published in the journal PLOS One, the scientists used a pair of engineered proteins to cut DNA in a site - specific manner to disrupt a targeted gene in the mosquito genomin the journal PLOS One, the scientists used a pair of engineered proteins to cut DNA in a site - specific manner to disrupt a targeted gene in the mosquito genomin a site - specific manner to disrupt a targeted gene in the mosquito genomin the mosquito genome.
In the laboratory, scientists can design specific guide RNAs that will show Cas9 where to cut twice, on both sides of the extra long stretch of C - A-G repeats in the HD genIn the laboratory, scientists can design specific guide RNAs that will show Cas9 where to cut twice, on both sides of the extra long stretch of C - A-G repeats in the HD genin the HD gene.