Sentences with phrase «cyclase c»

Its lead product candidate includes plecanatide a phase 3 guanylate cyclase C, or GC - C, receptor agonist, designed to treat GI disorders, primarily chronic idiopathic constipation, or CIC, and constipation - predominant irritable bowel syndrome, or IBS - C.

The primary source of cyclic GMP in the intestinal lining is called Guanylyl - cyclase C (GCC).

Not exact matches

Activated heterotrimers have a wide array of effectors including adenylate cyclase (AC), phospholipase C - beta, PI 3 - kinases, GIRK channels and RhoA