Sentences with phrase «cyclase in»

Not exact matches

In the presence of Gs alpha, the alpha subunit of the G protein that activates adenylyl cyclase, one form of adenylyl cyclase was inhibited by beta gamma, some forms were activated by beta gamma, and some forms were not affected by beta gamma.

This resulted in increased basal myocardial adenylyl cyclase activity, enhanced atrial contractility, and increased left ventricular function in vivo; these parameters at baseline in the transgenic animals were equal to those observed in control animals maximally stimulated with isoproterenol.

Adrenocorticotropin and epinephrine do not stimulate this adenyl cyclase, and very little cyclic phospho - diesterase activity is present in the membrane.

These findings support the concept that glucagon exerts its regulatory action in the liver by stimulating adenyl cyclase activity in the plasma membrane.

Although type I adenylyl cyclase is inhibited directly by exogenous beta gamma, inhibition of adenylyl cyclase by Gi alpha has not been convincingly demonstrated in vitro.

An adenylate cyclase that is activated specifically by very low concentrations of octopamine has been identified both in homogenates and in intact cells of the thoracic ganglia of an insect nervous system.

This enzyme appears to be distinct from two other adenylate cyclases present in the same tissue, which are activated by dopamine and by 5 - hydroxytryptamine, respectively.

Octopamine - Sensitive Adenylate Cyclase: Evidence for a Biological Role of Octopamine in Nervous Tissue

An adenyl cyclase activated by low concentrations of dopamine has been found in the mammalian superior cervical sympathetic ganglion.

Cigarette smoke activates guanylate cyclase and increases guanosine 3», 5» - monophosphate in tissues

Desensitized beta - adrenergic receptors showed a 40 to 50 percent reduction in their ability to couple to the heterologous adenylate cyclase system, comparable to the reduction in their functionality observed in their original membrane environment.

Studies of glutamate receptor channels expressed in cultured hippocampal pyramidal neurons reveal that these channels are subject to neuromodulatory regulation through the adenylate cyclase cascade.

A team of French and American scientists at several institutes pinpointed mutations in the retinal guanylate cyclase (RETGC) gene in eight families in which the disease has struck.

Both CB1 and D2 receptors couple to Gi - o proteins and inhibit adenylyl - cyclase, whereas their costimulation results in Gs protein - dependent activation of adenylyl - cyclase (44, 45).

Adenylyl Cyclase Type 5 (AC5): Knockout of AC5 extends life in mice, with the most plausible mechanism being increased resilience of the cardiovascular system to the various slings and arrows of aging.

Pituitary Adenylate Cyclase - activating Peptide (PACAP) Recruits Low Voltage - activated T - type Calcium Influx under Acute Sympathetic Stimulation in Mouse Adrenal Chromaffin Cells.

The primary source of cyclic GMP in the intestinal lining is called Guanylyl - cyclase C (GCC).

Some candidate virulence factors present in UM270 genome were detected and found to perform the following putative functions: a 3 - oxoacyl -[acyl - carrier - protein], catalase, capsule polysaccharide export, endoglucanase, cyclolysin secretion ATP - binding protein and diguanylate cyclase.

The effects of prior stress on anxiety - like responding to intra-BNST pituitary adenylate cyclase activating polypeptide in male and female rats King SB, Lezak KR, O'Reilly M, Toufexis DJ, Falls WA, Braas K, May V, Hammack SE.

Upon ligand binding, the Gs - coupled GPCR receptor activates adenylyl cyclase that in turn produces cAMP, governing important cellular responses.

Magnesium is a cofactor for several important enzymes in the body, like DNA / RNA polymerases, used to transcribe new DNA / RNA strands, and guanylate cyclase, used to regulate the movement of minerals across cell membranes.

Phen375 uses it to activate adenylyl cyclase and to raise cyclic AMP levels in your body cells.

The basic mechanism of action of forskolin is the activation of an enzyme, adenylate cyclase, which increases energy levels in cells.1 These enzymes are perhaps the most important cell - regulating compounds.