The newly developed CB1 receptor selective antagonist SR141716A was found to reverse cannabinoid agonist (WIN55212 - 2 or CP55940)- induced adenylyl
cyclase inhibition.
Not exact matches
Concentration - dependent
inhibition of adenylyl
cyclases by purified Gi alpha subunits is described.
Although type I adenylyl
cyclase is inhibited directly by exogenous beta gamma,
inhibition of adenylyl
cyclase by Gi alpha has not been convincingly demonstrated in vitro.
The Groups II and III of glutamate receptor membranes are coupled to the intracellular G - protein subunit, these mediate the
inhibition of adenylyl
cyclase [40, 41].